LOC105377490: A Potential Drug Target and Biomarker (G105377490)
LOC105377490: A Potential Drug Target and Biomarker
LOC105377490 is a novel gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique genetic sequence and expression patterns have piqued the interest of researchers, who are seeking new treatments and diagnostic tools.
The gene, named LOC105377490, is located on chromosome 18q22 and encodes a protein known as TLE3. TLE3 is a transmembrane protein that is involved in various cellular processes, including cell signaling, inflammation, and stress responses.
Recent studies have suggested that TLE3 may play a critical role in the development and progression of cancer. For example, TLE3 has been shown to be highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, TLE3 has been linked to the development of cancer-associated fibrosis, a condition that characterized by the excessive production of extracellular matrix proteins and the loss of stem cells.
As a potential drug target, TLE3 is being targeted by researchers to develop new treatments for various diseases. For example, researchers at the University of California, San Diego have identified a potential drug that targets TLE3 and may be useful for the treatment of cancer. The drug, called U219, is a small molecule that inhibits the activity of TLE3 and blocks the formation of stress granules, which are thought to play a role in the development of cancer.
In addition to its potential as a drug target, LOC105377490 has also been identified as a potential biomarker for cancer. The protein is expressed in various tissues and cells, including cancer cells, and its levels can be used as a diagnostic marker for cancer status. This makes it an attractive candidate for diagnostic applications, such as cancer detection and monitoring.
LOC105377490 has been shown to be expressed in various types of cancer, including breast, ovarian, and colorectal cancer. This suggests that it may be a useful biomarker for these diseases, and further research is needed to confirm its utility.
While more research is needed to fully understand the potential of LOC105377490 as a drug target and biomarker, its unique genetic sequence and expression patterns have already captured the attention of researchers. As the field of cancer research continues to evolve, it is likely that new treatments and diagnostic tools will emerge, and LOC105377490 will play an important role in the fight against this devastating disease.
Protein Name: Uncharacterized LOC105377490
The "LOC105377490 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105377490 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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