Target Name: LOC105378841
NCBI ID: G105378841
Review Report on LOC105378841 Target / Biomarker Content of Review Report on LOC105378841 Target / Biomarker
LOC105378841
Other Name(s): uncharacterized LOC105378841 | LOC105378841 variant X4 | Uncharacterized LOC105378841, transcript variant X4

LOC105378841: A Potential Drug Target and Biomarker

LOC105378841 is a novel gene that has been identified as a potential drug target and biomarker. The gene is located on chromosome 19q33 and encodes a protein known as CRLF2 (Cullin-3-Like 2). CRLF2 is a transmembrane protein that is involved in various cellular processes, including cell signaling, cell adhesion, and tissue development.

Based on the current research, it is suggested that CRLF2 may be a promising drug target due to its involvement in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Additionally, studies have shown that CRLF2 has been expressed in various tissues and cells , including human tissues, neuroblasts, and cancer cells.

One of the key advantages of CRLF2 as a drug target is its potential to intervene on various signaling pathways. For example, CRLF2 has been shown to be involved in the NF-kappa pathway, a well-known signaling pathway that plays a crucial role in cell signaling and development. NF-kappa signaling is involved in various processes, including cell growth, differentiation, and inflammation. Therefore, targeting CRLF2 may provide new insights into the mechanisms of these processes and potential therapeutic strategies.

Another potential benefit of CRLF2 as a drug target is its involvement in neurodegenerative diseases. As mentioned earlier, CRLF2 has been shown to be expressed in neuroblasts, which are a type of cell that is responsible for the production of neurotransmitters and other signaling molecules. Additionally , studies have shown that CRLF2 is involved in the production of ??-amyloid peptides, which are a hallmark of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Therefore, targeting CRLF2 in neuroblasts may provide new therapeutic strategies for the treatment of neurodegenerative diseases.

In addition to its potential therapeutic applications, CRLF2 is also a potential biomarker for various diseases. As mentioned earlier, CRLF2 has been shown to be involved in the production of ??-amyloid peptides, which are often used as a biomarker for Alzheimer's disease. Additionally , CRLF2 has been shown to be involved in the production of other peptides, including GLT-1, which is a potential biomarker for cancer. Therefore, targeting CRLF2 may provide new diagnostic tools for the diagnosis of various diseases, including cancer and neurodegenerative diseases.

Overall, LOC105378841 (CRLF2) is a promising drug target and biomarker that has the potential to revolutionize our understanding of various diseases. Further research is needed to fully understand the mechanisms of CRLF2's involvement in disease and to develop new therapeutic strategies. By targeting CRLF2, Researchers may be able to develop new treatments for cancer, neurodegenerative diseases, and other conditions that are currently untreated.

Protein Name: Uncharacterized LOC105378841

The "LOC105378841 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105378841 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

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