Regulation of Cellular Processes by ZRS-1 (G105804841)

Target Name: ZRS

NCBI ID: G105804841

Content of Review Report on ZRS Target / Biomarker

ZRS

Other Name(s): ZRS/LMBR1 | ZPA regulatory sequence | pZRS | MFCS1

Regulation of Cellular Processes by ZRS-1

ZRS (Zinc Finger Nucleases) are a family of proteins that play a crucial role in various cellular processes, including DNA replication, transcription, and gene expression. ZRS proteins are known to interact with a wide range of transcription factors, including DNA-binding proteins such as DNA polymerases, histone modifiers, and RNA-binding proteins.

The ZRS gene is located on chromosome 2 and encodes a protein named ZRS-1. ZRS-1 is a 21-kDa protein that contains a nucleotide-binding domain (NBD), a zinc finger domain (ZFD), and a carboxylic acid- containing tail (TTC). The NBD and ZFD are responsible for the protein's nuclear localization and stability, while the TTC is involved in the protein's stability and functions as a scaffold.

ZRS-1 has been shown to play a role in various cellular processes, including the regulation of gene expression, DNA replication, and chromosomal stability. For example, ZRS-1 has been shown to interact with the transcription factor p53, which is involved in the regulation of DNA replication and the expression of p53-controlled genes.

Additionally, ZRS-1 has been shown to play a role in the regulation of cell cycle progression. ZRS-1 has been shown to interact with the cyclin D1 protein, which is involved in the regulation of cell cycle progression. This interaction between ZRS- 1 and D1C suggest that ZRS-1 may be involved in the regulation of cell cycle progression.

Furthermore, ZRS-1 has been shown to play a role in the regulation of cellular signaling pathways. ZRS-1 has been shown to interact with the protein known as SIRT1, which is involved in the regulation of cellular signaling pathways. This interaction between ZRS -1 and SIRT1 suggest that ZRS-1 may be involved in the regulation of cellular signaling pathways.

ZRS-1 has also been shown to play a role in the regulation of inflammation. ZRS-1 has been shown to interact with the protein known as NF-kappa-B, which is involved in the regulation of inflammation. This interaction between ZRS-1 and NF-kappa-B suggests that ZRS-1 may be involved in the regulation of inflammation.

Despite the importance of ZRS-1 in various cellular processes, little is known about its specific functions or the mechanisms that regulate its activity. ZRS-1 has been shown to interact with a wide range of transcription factors, including DNA-binding proteins such as DNA polymerases, histone modifiers, and RNA binding proteins. It is possible that ZRS-1 functions as a negative regulator of these transcription factors, or as an activator of their activity.

In conclusion, ZRS-1 is a protein that has been shown to play a role in various cellular processes, including the regulation of gene expression, DNA replication, and chromosomal stability. ZRS-1 has also been shown to interact with a wide range of transcription factors, including DNA-binding proteins and RNA binding proteins. Further research is needed to determine the specific functions of ZRS-1 and the mechanisms that regulate its activity.

Protein Name: ZPA Regulatory Sequence

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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