Target Name: FAM107A
NCBI ID: G11170
Review Report on FAM107A Target / Biomarker Content of Review Report on FAM107A Target / Biomarker
FAM107A
Other Name(s): Actin-associated protein FAM107A (isoform a) | Protein FAM107A | protein FAM107A | Down-regulated in renal cell carcinoma 1 | TU3A | Actin-associated protein FAM107A | F107A_HUMAN | Protein TU3A | family with sequence similarity 107 member A | down-regulated in renal cell carcinoma 1 | DRR1 | FLJ30158 | Family with sequence similarity 107 member A, transcript variant 2 | Family with sequence similarity 107 member A transcript | FLJ45473 | FAM107A variant 2

FAM107A: A Potential Drug Target and Biomarker for Actin-Associated Protein

Actin-associated protein (FAM107A) is a protein that plays a crucial role in various cellular processes, including cell signaling, cytoskeletal organization, and chromatin structure. FAM107A is a member of the FAM107A family, which is characterized by the presence of a unique N-terminal domain called the FAM107A-specific domain. This domain is known to interact with various protein partners, including other actin proteins, to regulate cellular processes.

The search for potential drug targets and biomarkers has become a major focus in recent years, and FAM107A is an attractive candidate due to its unique function and the potential for modulating its activity. In this article, we will explore the potential of FAM107A as a drug target and biomarker.

FAM107A as a Drug Target

FAM107A has been shown to interact with several protein partners, including Myosin, a protein involved in muscle contraction and relaxation. These interactions suggest that FAM107A may play a role in regulating muscle activity and could potentially be a drug target for muscle-related diseases.

Studies have shown that FAM107A can modulate the activity of Myosin, leading to changes in muscle contraction and relaxation times. This modulation is dependent on the presence of FAM107A-specific domain, which is known to interact with the Myosin protein.

Additionally, FAM107A has been shown to interact with other proteins involved in cell signaling pathways, including the protein p21.p50, which is a known regulator of the T-cell receptor signaling pathway. This interaction suggests that FAM107A may play a role in regulating T-cell responses and could potentially be a drug target for T-cell-related diseases.

FAM107A as a Biomarker

FAM107A has also been shown to be a potential biomarker for various diseases, including cancer. This is because FAM107A is expressed in various tissues and can be used as a protein biomarker for cancer diagnosis and monitoring.

Studies have shown that FAM107A is expressed in various tissues, including cancer cells, and can be used as a protein biomarker for cancer diagnosis and monitoring. This is due to the fact that FAM107A is highly conserved across different species, which makes it a reliable protein biomarker.

FAM107A has also been shown to have potential utility as a diagnostic biomarker for various diseases, including cancer. This is due to the fact that FAM107A is expressed in various tissues and can be used as a protein biomarker for cancer diagnosis and monitoring.

Conclusion

In conclusion, FAM107A is a protein that has the potential to be a drug target and biomarker for various diseases. The unique FAM107A-specific domain and its interactions with various protein partners suggest that FAM107A may play a crucial role in regulating cellular processes and could be a valuable drug or biomarker for various diseases. Further research is needed to fully understand the potential of FAM107A as a drug target and biomarker.

Protein Name: Family With Sequence Similarity 107 Member A

Functions: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity). Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner (PubMed:20543869). Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner (PubMed:10564580, PubMed:28604741). May play a role in tumor development (PubMed:10564580)

The "FAM107A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM107A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FAM107B | FAM110A | FAM110B | FAM110C | FAM110D | FAM111A | FAM111A-DT | FAM111B | FAM114A1 | FAM114A2 | FAM117A | FAM117B | FAM118A | FAM118B | FAM120A | FAM120A2P | FAM120AOS | FAM120B | FAM120C | FAM124A | FAM124B | FAM131A | FAM131B | FAM131B-AS2 | FAM131C | FAM133A | FAM133B | FAM133CP | FAM133DP | FAM135A | FAM135B | FAM136A | FAM136BP | FAM138A | FAM138B | FAM138C | FAM138D | FAM138F | FAM13A | FAM13A-AS1 | FAM13B | FAM13C | FAM149A | FAM149B1 | FAM151A | FAM151B | FAM153A | FAM153B | FAM153CP | FAM156A | FAM157A | FAM157B | FAM157C | FAM161A | FAM161B | FAM162A | FAM162B | FAM163A | FAM163B | FAM166A | FAM166B | FAM166C | FAM167A | FAM167A-AS1 | FAM167B | FAM168A | FAM168B | FAM169A | FAM169BP | FAM170A | FAM170B | FAM170B-AS1 | FAM171A1 | FAM171A2 | FAM171B | FAM172A | FAM172BP | FAM174A | FAM174B | FAM174C | FAM177A1 | FAM177B | FAM178B | FAM180A | FAM180B | FAM181A | FAM181B | FAM182A | FAM182B | FAM183A | FAM183BP | FAM184A | FAM184B | FAM185A | FAM185BP | FAM186A | FAM186B | FAM187B | FAM187B2P | FAM193A