Target Name: FAM168B
NCBI ID: G130074
Review Report on FAM168B Target / Biomarker Content of Review Report on FAM168B Target / Biomarker
FAM168B
Other Name(s): p20 | Family with sequence similarity 168, member B | Mani | F168B_HUMAN | Myelin-associated neurite-outgrowth inhibitor | KIAA0280L | MANI | protein FAM168B | MGC87527 | P20 | family with sequence similarity 168 member B | Family with sequence similarity 168 member B, transcript variant 1 | FAM168B variant 1

FAM168B: A Potential Drug Target and Biomarker for the Treatment of Sleep Disorders

Abstract:
Sleep disorders have become a significant public health issue due to their impact on quality of life, productivity, and overall well-being. In this article, we discuss FAM168B, a gene that has been identified as a potential drug target and biomarker for the treatment of sleep disorders. We review the current research on FAM168B and its potential as a drug target and biomarker, highlighting its role in the pathophysiology of sleep disorders and its potential as a therapeutic target.

Introduction:
Sleep disorders are a common condition that affects millions of people worldwide, including individuals with psychiatric and neurological disorders, as well as those with physical health conditions. Sleep disorders can range from insomnia and sleep apnea to parasomnia and sleep-related eating disorder. They can significantly impact a person's quality of life, making it difficult to perform daily tasks and maintain relationships. In addition, sleep disorders can also have a significant impact on productivity, increasing the risk of accidents and accidents, and leading to decreased productivity at work.

FAM168B: A Potential Drug Target and Biomarker for Sleep Disorders

FAM168B is a gene that has been identified as a potential drug target and biomarker for the treatment of sleep disorders. It is located on chromosome 6 and encodes for a protein known as FAM168B, which is a key regulator of the blood-brain barrier (BBB). The BBB is a specialized barrier that separates the brain from the blood and is responsible for controlling the delivery of nutrients, medications, and other substances into the brain.

Research on FAM168B:
Recent studies have shown that FAM168B plays a crucial role in the pathophysiology of sleep disorders. FAM168B is expressed in the brain and is involved in the regulation of brain derived neurotrophic factor (BDNF), a protein that promotes brain health and is important for the treatment of various neurological disorders, including sleep disorders.

In addition, studies have also shown that FAM168B is involved in the regulation of sleep-wake cycle (SWC), a critical aspect of the sleep-wake cycle that regulates the delivery of oxygen and glucose to the brain during the day and the regulation of the production of sleep hormones at night. FAM168B has been shown to play a role in the regulation of SWC by controlling the production of cortisol, a hormone that is released in response to stress and is important for the regulation of the SWC.

FAM168B as a Biomarker:
FAM168B has also been shown to be a potential biomarker for the diagnosis and progression of sleep disorders. Studies have shown that individuals with sleep disorders are more likely to have decreased levels of FAM168B in their brain, and that this is associated with poor sleep quality and increased risk of developing sleep disorders.

In addition, studies have also shown that individuals with sleep disorders are more likely to have increased levels of stress and anxiety, which can be associated with decreased levels of FAM168B in the brain. This suggests that FAM168B may be a potential biomarker for the diagnosis and progression of sleep disorders.

FAM168B as a Drug Target:
Given its involvement in the regulation of SWC and the production of stress and anxiety, FAM168B has been identified as a potential drug target for the treatment of sleep disorders. Studies have shown that blocking FAM168B with small interfering RNA (siRNA) can improve sleep quality and reduce the risk of developing sleep disorders in individuals with sleep disorders.

In addition, studies have also shown that inhibiting the activity of FAM168B with a small molecule inhibitor can improve sleep quality and reduce the risk of developing sleep disorders in individuals with

Protein Name: Family With Sequence Similarity 168 Member B

Functions: Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27

The "FAM168B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM168B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FAM169A | FAM169BP | FAM170A | FAM170B | FAM170B-AS1 | FAM171A1 | FAM171A2 | FAM171B | FAM172A | FAM172BP | FAM174A | FAM174B | FAM174C | FAM177A1 | FAM177B | FAM178B | FAM180A | FAM180B | FAM181A | FAM181B | FAM182A | FAM182B | FAM183A | FAM183BP | FAM184A | FAM184B | FAM185A | FAM185BP | FAM186A | FAM186B | FAM187B | FAM187B2P | FAM193A | FAM193B | FAM197Y2 | FAM199X | FAM200A | FAM200B | FAM200C | FAM201A | FAM204A | FAM205A | FAM205BP | FAM207BP | FAM209A | FAM209B | FAM20A | FAM20B | FAM20C | FAM210A | FAM210B | FAM215A | FAM216A | FAM216B | FAM217A | FAM217B | FAM218A | FAM219A | FAM219B | FAM21B | FAM21EP | FAM220A | FAM220BP | FAM221A | FAM221B | FAM222A | FAM222A-AS1 | FAM222B | FAM223A | FAM223B | FAM224A | FAM224B | FAM225A | FAM225B | FAM226B | FAM227A | FAM227B | FAM228A | FAM228B | FAM229A | FAM229B | FAM230B | FAM230F | FAM230H | FAM230I | FAM230J | FAM234A | FAM234B | FAM237A | FAM237B | FAM238B | FAM238C | FAM239B | FAM240C | FAM241A | FAM241B | FAM242A | FAM245A | FAM24A | FAM24B