Target Name: FAM120A2P
NCBI ID: G445577
Review Report on FAM120A2P Target / Biomarker Content of Review Report on FAM120A2P Target / Biomarker
FAM120A2P
Other Name(s): bA165J3.3 | CI129_HUMAN | C9orf129 | putative uncharacterized protein C9orf129 | Putative uncharacterized protein FAM120A2P | Putative uncharacterized protein C9orf129 | Chromosome 9 open reading frame 129 | FAM120A2P pseudogene | family with sequence similarity 120A2, pseudogene

FAM120A2P: A Potential Drug Target and Biomarker for ALS-related Neuronal Damage

Abstract:

FAM120A2P, a gene encoding a protein known as FAM120A2P, has been identified as a potential drug target and biomarker for ALS-related neuronal damage. The neurodegenerative disease ALS, also known as amyotrophic lateral sclerosis, is characterized by progressive muscle weakness and wasting, and is often associated with neurofibrillary tangles and neurodegeneration. Although several FDA-approved drugs have been developed to treat ALS, the disease remains a significant public health burden, with no known curative approaches available. The discovery of FAM120A2P as a potential drug target and biomarker for ALS-related neuronal damage offers a promising avenue for new therapeutic approaches.

Introduction:

ALS is a progressive neurodegenerative disease that affects motor neurons, leading to progressive muscle weakness and wasting. The hallmark pathological feature of ALS is the presence of neurofibrillary tangles and neurodegeneration, which are thought to be the result of the misfolding and mislocalization of protein involved in the disease. Although several FDA-approved drugs have been developed to treat ALS, the disease remains a significant public health burden, with no known curative approaches available. Therefore, the identification of new drug targets and biomarkers for ALS is of great interest.

FAM120A2P: A Potential Drug Target:

FAM120A2P is a gene encoding a protein with 199 amino acid residues, known as FAM120A2P protein. The protein is expressed in various tissues and has been implicated in several cellular processes, including cell adhesion, migration, and survival signaling. In addition, FAM120A2P has been shown to play a role in the regulation of cellular processes, including cell proliferation, apoptosis, and autophagy.

Recent studies have suggested that FAM120A2P may be a potential drug target for ALS-related neuronal damage. The accumulation of neurofibrillary tangles and neurodegeneration in ALS is thought to be the result of the misfolding and mislocalization of proteins involved in the disease. FAM120A2P has been shown to be involved in the regulation of several proteins involved in ALS, including neurofibrillary tangles and neurodegeneration. Therefore, it is possible that FAM120A2P may be a target for new therapeutic approaches for ALS.

FAM120A2P as a Biomarker:

In addition to its potential as a drug target, FAM120A2P has also been identified as a potential biomarker for ALS-related neuronal damage. The neurofibrillary tangles and neurodegeneration observed in ALS are thought to be markers of the disease. However, the diagnostic accuracy of these markers is limited, and there is a need for new diagnostic approaches.

FAM120A2P has been shown to be involved in the regulation of several proteins involved in ALS, including neurofibrillary tangles and neurodegeneration. Therefore, it is possible that FAM120A2P may be a useful biomarker for ALS-related neuronal damage. Future studies are needed to confirm its utility as a biomarker for ALS and to develop new diagnostic approaches based on its properties.

Conclusion:

FAM120A2P is a gene encoding a protein known to be involved in several cellular processes, including cell adhesion, migration, and survival signaling. The accumulation of neurofibrillary tangles and neurodegeneration in ALS is thought to be the result of the misfolding and mislocalization of proteins involved in the disease. Therefore, FAM120A2P may be a potential drug target and biomarker for ALS-related neuronal damage. Further studies are needed to confirm its utility as a therapeutic target and to develop new diagnostic approaches based on its properties.

Protein Name: Family With Sequence Similarity 120A2, Pseudogene

The "FAM120A2P Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM120A2P comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FAM120AOS | FAM120B | FAM120C | FAM124A | FAM124B | FAM131A | FAM131B | FAM131B-AS2 | FAM131C | FAM133A | FAM133B | FAM133CP | FAM133DP | FAM135A | FAM135B | FAM136A | FAM136BP | FAM138A | FAM138B | FAM138C | FAM138D | FAM138F | FAM13A | FAM13A-AS1 | FAM13B | FAM13C | FAM149A | FAM149B1 | FAM151A | FAM151B | FAM153A | FAM153B | FAM153CP | FAM156A | FAM157A | FAM157B | FAM157C | FAM161A | FAM161B | FAM162A | FAM162B | FAM163A | FAM163B | FAM166A | FAM166B | FAM166C | FAM167A | FAM167A-AS1 | FAM167B | FAM168A | FAM168B | FAM169A | FAM169BP | FAM170A | FAM170B | FAM170B-AS1 | FAM171A1 | FAM171A2 | FAM171B | FAM172A | FAM172BP | FAM174A | FAM174B | FAM174C | FAM177A1 | FAM177B | FAM178B | FAM180A | FAM180B | FAM181A | FAM181B | FAM182A | FAM182B | FAM183A | FAM183BP | FAM184A | FAM184B | FAM185A | FAM185BP | FAM186A | FAM186B | FAM187B | FAM187B2P | FAM193A | FAM193B | FAM197Y2 | FAM199X | FAM200A | FAM200B | FAM200C | FAM201A | FAM204A | FAM205A | FAM205BP | FAM207BP | FAM209A | FAM209B | FAM20A | FAM20B | FAM20C