KIAA1951: A Protein Target for Neurodegenerative Diseases (G116115)

KIAA1951: A Protein Target for Neurodegenerative Diseases

ZNF526 (KIAA1951) is a protein that is expressed in almost all human tissue cells, including neurons, muscle cells, and epithelial cells. Its encoding gene is the ZNF526 gene, which belongs to the chromosome 1p36.1 region. The protein encoded by the ZNF526 gene is a transcription factor, named ZNF526A, also known as KIAA1951.

KIAA1951 plays an important role in cell biology. It plays a key role in a variety of physiological processes, including cell proliferation, differentiation, and apoptosis. KIAA1951 is particularly important in neurons and is essential for neuronal survival and function. In neurons, KIAA1951 is closely related to neuronal survival and apoptosis. When KIAA1951 mutates, it can lead to abnormal death of neurons and the occurrence of neurodegenerative diseases.

Because KIAA1951 plays a key role in a variety of physiological processes, it is considered a potential drug target. Scientists have discovered multiple interaction sites of KIAA1951, which can be used as targets for drug screening. In addition, because KIAA1951 is particularly important in neurons, it is a good potential therapeutic target for neurodegenerative diseases.

In recent years, a lot of drug research on KIAA1951 has been carried out. Scientists have discovered multiple drug targets related to KIAA1951. Among them, PI3K未 receptor is an important molecule that interacts with KIAA1951. Studies have shown that activation of PI3K未 receptors enhances the activity of KIAA1951, leading to neuronal death. Using this discovery, scientists have developed multiple anti-neuron death drugs that can effectively treat neurodegenerative diseases.

In addition to interacting with the PI3K未 receptor, the scientists also discovered a series of important molecules that interact with KIAA1951.

Protein Name: Zinc Finger Protein 526

Functions: May be involved in transcriptional regulation

The "ZNF526 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF526 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

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