Target Name: ZNF618
NCBI ID: G114991
Review Report on ZNF618 Target / Biomarker Content of Review Report on ZNF618 Target / Biomarker
ZNF618
Other Name(s): FP13169 | zinc finger protein 618 | Zinc finger protein 618 (isoform 1) | ZNF618 variant 1 | Zinc finger protein 618, transcript variant 1 | Neural precursor cell expressed, developmentally down-regulated 10 | neural precursor cell expressed, developmentally down-regulated 10 | Zinc finger protein 618 | ZN618_HUMAN | KIAA1952 | NEDD10

ZNF618: Key Regulator of Neuronal Development and Function

ZNF618 (Fp13169) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ZNF6 gene family, which is known for its role in regulating gene expression and cell proliferation. ZNF618 is a key regulator of neuronal development and function, and is thought to play a role in a variety of neurological and cardiovascular disorders.

The ZNF618 protein is composed of 174 amino acid residues, and has a calculated molecular weight of 19.8 kDa. It is expressed in a variety of tissues, including the brain, heart, and kidneys, and is also found in the placenta and testes. ZNF618 is a transcription factor that has been shown to play a role in the regulation of gene expression in a variety of cell types.

One of the most interesting aspects of ZNF618 is its role in neuronal development and function. Neurons are highly specialized cells that are responsible for transmitting electrical signals throughout the body. They are formed during fetal development, and their properties and functions are regulated by a complex interplay of genetic and environmental factors. ZNF618 is thought to be involved in this process, as it has been shown to play a role in the regulation of neuronal stem cell proliferation and differentiation.

In addition to its role in neuronal development, ZNF618 is also thought to be involved in the regulation of cellular signaling pathways. For example, it has been shown to play a role in the regulation of the TGF-β pathway, a well-known regulator of cell growth and differentiation. TGF-β is a potent signaling pathway that is involved in the development and maintenance of tissues and organs, and is thought to play a key role in the regulation of many diseases, including cancer, neurodegenerative diseases, and developmental disorders. ZNF618 is thought to be involved in the regulation of TGF-β activity, which could have important implications for the understanding and treatment of these diseases.

Another promising aspect of ZNF618 is its potential as a drug target. The regulation of gene expression by transcription factors is a key aspect of many diseases, including cancer, neurodegenerative diseases, and developmental disorders. Targeting the activity of these transcription factors has the potential to be a highly effective way to treat these diseases. ZNF618 is a potential drug target, as it has been shown to play a role in the regulation of cellular signaling pathways, and is thought to be involved in the regulation of neuronal development and function.

In conclusion, ZNF618 is a protein that is expressed in various tissues of the body, and is known for its role in the regulation of gene expression and cell proliferation. It is also thought to play a key role in the regulation of neuronal development and function, and is a potential drug target for the treatment of a variety of neurological and cardiovascular disorders. Further research is needed to fully understand the role of ZNF618 in these processes, and to develop effective treatments for the associated diseases.

Protein Name: Zinc Finger Protein 618

Functions: Regulates UHRF2 function as a specific 5-hydroxymethylcytosine (5hmC) reader by regulating its chromatin localization

The "ZNF618 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF618 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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