The LIN54 Protein: A Drug Target and Potential Biomarker for Neurological Disorders

Target Name: LIN54

NCBI ID: G132660

LIN54

The LIN54 Protein: A Drug Target and Potential Biomarker for Neurological Disorders

The LIN54 protein, also known as the lin-54 DREAM MuvB core complex component, is a protein that plays a critical role in the development and maintenance of neural stem cells. It is a key component of the MuvB complex, which is a protein complex that helps to maintain the stem-like properties of neural stem cells. The LIN54 protein has been shown to be a drug target and may also be a biomarker for the treatment of various neurological and psychiatric disorders.

The LIN54 protein is a transmembrane protein that is expressed in a variety of tissues, including the brain, spinal cord, and peripheral tissues. It is made up of 115 amino acid residues and has a calculated molecular weight of 17.9 kDa. The LIN54 protein is typically expressed in neural stem cells and is involved in the development and maintenance of these cells.

One of the key functions of the LIN54 protein is its role in the MuvB complex. The MuvB complex is a protein complex that is involved in the maintenance of stem-like properties in neural stem cells. The LIN54 protein is a key component of this complex and helps to keep the stem-like properties of neural stem cells alive.

The LIN54 protein is involved in several different processes in the MuvB complex. It helps to maintain the stability of the complex by interacting with the proteins that are present in the complex. It also plays a role in the regulation of the activity of the other proteins in the complex.

One of the key functions of the LIN54 protein is its ability to interact with the protein known as KLF1. KLF1 is a key regulator of the stem-like properties of neural stem cells and is involved in the development and maintenance of these cells. The LIN54 protein helps to maintain the activity of KLF1 and this protein is important for the maintenance of the stem-like properties of neural stem cells.

Another function of the LIN54 protein is its role in the regulation of the activity of the transcription factor, Nrf2. Nrf2 is a protein that is involved in the regulation of gene expression and is important for the development and maintenance of neural stem cells. The LIN54 protein helps to regulate the activity of Nrf2 and this protein is important for the maintenance of the stem-like properties of neural stem cells.

In addition to its role in the MuvB complex, the LIN54 protein has also been shown to have a variety of different functions in neural stem cells. For example, it is involved in the regulation of the activity of the protein known as Twi-2, which is involved in the development and maintenance of neural stem cells. The LIN54 protein also plays a role in the regulation of the activity of the protein known as FoxO3, which is involved in the development and maintenance of neural stem cells.

The LIN54 protein has also been shown to have a variety of different effects on neural stem cells. For example, it is involved in the regulation of the activity of the protein known as p53, which is a protein that is involved in the regulation of gene expression. The LIN54 protein helps to regulate the activity of p53 and this protein is important for the development and maintenance of neural stem cells.

In addition to its effects on neural stem cells, the LIN54 protein has also been shown to have a variety of different effects on other cells and tissues. For example, it is involved in the regulation of the activity of the protein known as NF-kappa-B, which is a protein that is involved in the regulation of inflammation and immune responses. The LIN54 protein helps to regulate the activity of NF-kappa-B and this protein is important for the regulation of inflammation and immune responses.

The LIN54 protein is also involved in the regulation of the activity of the protein known as

Protein Name: Lin-54 DREAM MuvB Core Complex Component

Functions: Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context (PubMed:17671431, PubMed:17531812). In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes (PubMed:17671431, PubMed:17531812). In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation (PubMed:17671431, PubMed:17531812). In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner (PubMed:19725879). Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA (PubMed:27465258)

The "LIN54 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LIN54 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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