LINC00382: A Potential Drug Target and Biomarker (G101927195)

Target Name: LINC00382

NCBI ID: G101927195

LINC00382

Other Name(s): Long intergenic non-protein coding RNA 382 | TCONS_00021500 | long intergenic non-protein coding RNA 382

LINC00382: A Potential Drug Target and Biomarker

LINC00382 is a non-protein coding RNA (ncRNA) molecule that has been identified using RNA sequencing (RNA-seq) data. It is located within the last exon of the gene HSP701, which encodes a protein involved in the detoxification of xenobiotics. HSP701 is a heat shock protein (HSP) that is expressed in a variety of tissues and cells, including the liver, muscle, and brain. The function of HSP701 in these cells is to protect them from the harmful effects of xenobiotics, which are drugs or other substances that can cause cellular damage.

The RNA-seq data suggests that LINC00382 is highly expressed in the liver, muscle, and brain of RNA-seq samples from mice that have been treated with a variety of xenobiotics. It is also highly expressed in human tissue samples that have been treated with these drugs. This suggests that LINC00382 may be a drug target or biomarker for xenobiotics.

Drug Target

The potential drug target for LINC00382 is the HSP701 protein. HSP701 is a heat shock protein that is involved in the detoxification of xenobiotics, which can cause cellular damage. The HSP701 protein is expressed in a variety of tissues and cells, including the liver, muscle, and brain. It is thought to play a role in protecting these cells from the harmful effects of xenobiotics.

The drug target for LINC00382 may be the HSP701 protein by modulating its expression levels or activity. This could lead to the inhibition of the HSP701 protein's ability to protect cells from the harmful effects of xenobiotics. This could potentially lead to the development of a treatment for xenobiotics-induced cellular damage.

Biomarker

LINC00382 may also be a biomarker for xenobiotics. The high expression of LINC00382 in the liver, muscle, and brain of RNA-seq samples treated with xenobiotics suggests that it may be a reliable biomarker for these tissues. This could potentially be used to monitor the effectiveness of a treatment for xenobiotics-induced cellular damage.

Conclusion

The potential drug target for LINC00382 is the HSP701 protein, which is involved in the detoxification of xenobiotics. The high expression of LINC00382 in the liver, muscle, and brain of RNA-seq samples treated with xenobiotics suggests that it may be a reliable biomarker for these tissues. Further research is needed to determine the mechanism of action of LINC00382 and to explore its potential as a drug target or biomarker for xenobiotics.

Protein Name: Long Intergenic Non-protein Coding RNA 382

The "LINC00382 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC00382 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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