CSF 50kD Subunit: Key Component of Protein, Regulates Gene Expression and Cellular Processes

Target Name: CSTF1

NCBI ID: G1477

CSTF1

CSF 50kD Subunit: Key Component of Protein, Regulates Gene Expression and Cellular Processes

Cleavage stimulation factor (CSF) is a protein that plays a critical role in the development and maintenance of tissues. CSF is a 3' pre-RNA and is composed of four subunits. It is one of the key factors in the regulation of gene expression and has been implicated in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The 50kD subunit of CSF is a key component of the protein and is responsible for the majority of its 50kDa protein mass. The 50kDa subunit is composed of two domains, an N-terminal domain and a C-terminal domain. The N-terminal domain is responsible for the protein's stability and is involved in the formation of a complex with the transcription factor, pRCH2. The C-terminal domain is responsible for the protein's stability and is involved in the formation of a complex with the protein, p120Gsk.

CSF has been shown to play a role in the regulation of gene expression in various organisms, including humans. For example, studies have shown that CSF can promote the expression of genes involved in cell adhesion, migration and invasion, and has been implicated in the development of various diseases, including cancer.

In addition to its role in gene expression, CSF has also been shown to play a role in the regulation of cellular processes. For example, studies have shown that CSF can promote the formation of mitochondrial organelles and can also inhibit the activity of the protein, p16INK4a, which is involved in cell cycle progression.

The 50kD subunit of CSF has also been shown to play a role in the regulation of cellular signaling pathways. For example, studies have shown that the 50kDa subunit can interact with the protein, Src, and can also promote the formation of a protein complex with the protein, Yes/Yy.

In conclusion, the 50kD subunit of CSF is a key component of the protein and plays a critical role in the regulation of gene expression and cellular processes. Its role in these processes makes it an attractive drug target and may have implications for the treatment of various diseases. Further research is needed to fully understand the mechanisms of CSF and its potential as a drug target.

Protein Name: Cleavage Stimulation Factor Subunit 1

Functions: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (PubMed:10669729). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (PubMed:10669729)

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