Target Name: CTSE
NCBI ID: G1510
Review Report on CTSE Target / Biomarker Content of Review Report on CTSE Target / Biomarker
CTSE
Other Name(s): CATE_HUMAN | cathepsin E | Cathepsin E (isoform a) | Cathepsin E, transcript variant 1 | CTSE variant 1 | Erythrocyte membrane aspartic proteinase | erythrocyte membrane aspartic proteinase | Cathepsin E isoform a preproprotein | Slow-moving proteinase | Cathepsin E form II | slow-moving proteinase | Cathepsin E form I | Cathepsin E | CATE

CTSE: A Potential Drug Target for Alzheimer's and Cancer

CTSE (CATE_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the catenin family, which is a group of transmembrane proteins that play a variety of roles in various biological processes.

One of the unique features of CTSE is its ability to interact with several different molecules, including cytoskeletal components, actinin, and the protein tau. This interaction with these molecules makes CTSE a potential drug target or biomarker for a variety of diseases.

One of the most promising aspects of CTSE is its potential as a drug target for Alzheimer's disease. Alzheimer's disease is a progressive neurodegenerative disorder that is characterized by the accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain. These tangles and plaques are thought to contribute to the destruction of nerve cells in the brain, leading to the symptoms of Alzheimer's disease.

Research has shown that CTSE is involved in the formation of these neurofibrillary tangles and beta-amyloid plaques in the brain. Studies have also shown that inhibiting the activity of CTSE has the potential to reduce the formation of these tangles and plaques, which could lead to a potential treatment for Alzheimer's disease.

Another potential application of CTSE as a drug target is its role in the regulation of cell division. CTSE is a component of the cytoskeleton, which is responsible for the structure and stability of the cell. It is known to play a role in the regulation of Studies of cell division, and altered levels of CTSE have been observed in various types of cancer.

The potential implications of these studies are that CTSE may be a useful biomarker or drug target for the diagnosis and treatment of certain types of cancer. Further research is needed to fully understand the role of CTSE in these processes and to develop effective treatments.

Protein Name: Cathepsin E

Functions: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain

The "CTSE Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CTSE comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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CTSF | CTSG | CTSH | CTSK | CTSL | CTSL3P | CTSLP2 | CTSLP3 | CTSLP6 | CTSLP8 | CTSO | CTSS | CTSV | CTSW | CTSZ | CTTN | CTTNBP2 | CTTNBP2NL | CTU1 | CTU2 | CTXN1 | CTXN2 | CTXN3 | CTXND1 | CTXND2 | CUBN | CUBNP2 | CUEDC1 | CUEDC2 | CUL1 | CUL2 | CUL3 | CUL4A | CUL4B | CUL5 | CUL7 | CUL9 | Cullin | CUTA | CUTALP | CUTC | CUX1 | CUX2 | CUZD1 | CWC15 | CWC22 | CWC25 | CWC27 | CWF19L1 | CWF19L2 | CWH43 | CX3CL1 | CX3CR1 | CXADR | CXADRP1 | CXADRP2 | CXADRP3 | CXCL1 | CXCL10 | CXCL11 | CXCL12 | CXCL13 | CXCL14 | CXCL16 | CXCL17 | CXCL2 | CXCL3 | CXCL5 | CXCL6 | CXCL8 | CXCL9 | CXCR1 | CXCR2 | CXCR2P1 | CXCR3 | CXCR4 | CXCR5 | CXCR6 | CXorf30 | CXorf38 | CXorf49 | CXorf49B | CXorf51A | CXorf51B | CXorf58 | CXorf65 | CXorf66 | CXXC1 | CXXC1P1 | CXXC4 | CXXC4-AS1 | CXXC5 | CYB561 | CYB561A3 | CYB561D1 | CYB561D2 | CYB5A | CYB5B | CYB5D1 | CYB5D2