Target Name: DLX5
NCBI ID: G1749
Review Report on DLX5 Target / Biomarker Content of Review Report on DLX5 Target / Biomarker
DLX5
Other Name(s): split hand/foot malformation type 1 with sensorineural hearing loss | DLX5_HUMAN | Distal-less homeobox 5 | Homeobox protein DLX-5 | SHFM1 | SHFM1D | distal-less homeo box 5 | distal-less homeobox 5 | Distal-less homeo box 5

DLX5: A Potential Drug Target and Biomarker

DLX5 is a protein that is expressed in various tissues and cells throughout the body. Its function is not well understood, but it is known to play a role in the development and progression of various diseases, including cancer. As a result, DLX5 has become a focus of interest for researchers looking for new treatments for these diseases. In this article, we will explore the potential implications of DLX5 as a drug target and biomarker.

The Importance of DLX5

DLX5 is a protein that is expressed in many tissues throughout the body, including the brain, heart, liver, and muscle. It is a small protein that is made up of only 114 amino acids. Despite its small size, DLX5 has been shown to play a critical role in the development and progression of various diseases.

One of the most significant functions of DLX5 is its role in cancer development. Many studies have shown that high levels of DLX5 are associated with the development and progression of cancer. For example, a study published in the journal Oncogene found that high levels of DLX5 were associated with poor prognosis in patients with pancreatic cancer.

In addition to its role in cancer development, DLX5 has also been shown to play a role in the regulation of cell signaling pathways. It has been shown to interact with a variety of signaling molecules, including TGF-β1, a key regulator of cell signaling pathways.

The Potential Implications of DLX5 as a Drug Target

IfDLX5 turns out to be a drug target, it could lead to the development of new treatments for a variety of diseases. Because DLX5 is involved in the regulation of cell signaling pathways, any treatments that target this pathway could potentially be effective in treating a wide range of diseases.

One of the most promising aspects of targeting DLX5 is the use of small molecules as therapeutic agents. Because DLX5 is a protein that is expressed in many tissues throughout the body, it is possible to use small molecules that are similar to those that are naturally occurring in the body to target it. This approach has the advantage of being able to selectively target a protein without affecting other proteins in the body.

Another promising aspect of targeting DLX5 is the potential use of gene editing techniques to modify its expression levels. This could allow researchers to specifically reduce the levels of DLX5 in certain tissues or cells, such as cancer cells, without affecting the levels of DLX5 in other tissues or cells.

The Potential Implications of DLX5 as a Biomarker

In addition to its potential as a drug target, DLX5 is also a potential biomarker for the development and progression of various diseases. Because it is involved in the regulation of cell signaling pathways, any changes in the levels of DLX5 in certain tissues or cells could be an indication of the presence of a particular disease.

One of the most promising aspects of using DLX5 as a biomarker is its potential to be used in the early detection of diseases. Because DLX5 is expressed in many tissues throughout the body, any changes in its levels could be an indication of the presence of a particular disease, such as cancer. This could allow for the early detection of diseases and the development of new treatments.

Another promising aspect of using DLX5 as a biomarker is its potential to be used in the monitoring of disease progression. Because its levels are affected by various factors, such as the presence of certain genetic mutations, the levels of DLX5 in certain tissues or cells could be used to track the progression of a particular disease. This could allow for the monitoring of disease

Protein Name: Distal-less Homeobox 5

Functions: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding

The "DLX5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DLX5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DLX6 | DLX6-AS1 | DM1-AS | DMAC1 | DMAC2 | DMAC2L | DMAP1 | DMBT1 | DMBT1L1 | DMBX1 | DMC1 | DMD | DMGDH | DMKN | DMP1 | DMPK | DMRT1 | DMRT2 | DMRT3 | DMRTA1 | DMRTA2 | DMRTB1 | DMRTC1 | DMRTC1B | DMRTC2 | DMTF1 | DMTF1-AS1 | DMTN | DMWD | DMXL1 | DMXL2 | DNA ligase | DNA Methyltransferase (DNMT) | DNA Polymerase alpha | DNA polymerase delta | DNA Polymerase epsilon | DNA Polymerase gamma | DNA Polymerase zeta Complex | DNA primase | DNA topoisomerase | DNA Topoisomerase II | DNA-Dependent Protein Kinase (DNA-PK) | DNA-Directed DNA Polymerase Complex | DNA-Directed RNA Polymerase | DNA-Directed RNA Polymerase I | DNA-Directed RNA Polymerase II | DNA-directed RNA polymerase II, core complex | DNA-directed RNA polymerase III | DNA2 | DNAAF1 | DNAAF10 | DNAAF11 | DNAAF2 | DNAAF3 | DNAAF4 | DNAAF4-CCPG1 | DNAAF5 | DNAAF6 | DNAAF8 | DNAAF9 | DNAH1 | DNAH10 | DNAH11 | DNAH12 | DNAH14 | DNAH17 | DNAH17-AS1 | DNAH2 | DNAH3 | DNAH5 | DNAH6 | DNAH7 | DNAH8 | DNAH8-AS1 | DNAH9 | DNAI1 | DNAI2 | DNAI3 | DNAI4 | DNAI7 | DNAJA1 | DNAJA1P3 | DNAJA1P4 | DNAJA1P5 | DNAJA2 | DNAJA3 | DNAJA4 | DNAJB1 | DNAJB11 | DNAJB12 | DNAJB13 | DNAJB14 | DNAJB2 | DNAJB3 | DNAJB4 | DNAJB5 | DNAJB6 | DNAJB6P1 | DNAJB7 | DNAJB8