Target Name: DMAC2
NCBI ID: G55101
Review Report on DMAC2 Target / Biomarker Content of Review Report on DMAC2 Target / Biomarker
DMAC2
Other Name(s): DMAC2 variant 5 | Distal membrane arm assembly component 2, transcript variant 11 | DMAC2 variant 2 | Distal membrane-arm assembly complex protein 2 (isoform 10) | Distal membrane-arm assembly complex protein 2 | DMAC2_HUMAN | DMAC2 variant 6 | DMAC2 variant 3 | ATP synthase subunit s-like protein | Distal membrane arm assembly component 2, transcript variant 1 | Distal membrane arm assembly component 2, transcript variant 6 | Distal membrane-arm assembly complex protein 2 (isoform 3) | Distal membrane arm assembly component 2, transcript variant 10 | distal membrane arm assembly component 2 | Distal membrane arm assembly component 2, transcript variant 2 | Distal membrane arm assembly component 2, transcript variant 5 | distal membrane arm assembly complex 2 | Distal membrane arm assembly component 2, transcript variant 4 | DMAC2 variant 11 | ATP5SL | Distal membrane-arm assembly complex protein 2 (isoform 6) | DMAC2 variant 10 | Distal membrane-arm assembly complex protein 2 (isoform 5) | DMAC2 variant 4 | Distal membrane-arm assembly complex protein 2 (isoform 4) | ATP5S like | Distal membrane-arm assembly complex protein 2 (isoform 2) | Distal membrane-arm assembly complex protein 2 (isoform 1) | Distal membrane-arm assembly complex protein 2 (isoform 9) | Distal membrane arm assembly component 2, transcript variant 3 | FLJ10241 | DMAC2 variant 1

DMAC2: A Potential Drug Target for Neurological Disorders

DMAC2 (doublecortin) is a protein that is expressed in the brain and is involved in the development and maintenance of neuronal connections. It is a potential drug target and has been identified as a biomarker for several neurological disorders, including Alzheimer's disease.

DMAC2 is a member of the superfamily of proteins that are known as the T-type Ca2+ channels. These channels are involved in the regulation of muscle and nerve contractions and are thought to play a role in the development of certain neurological disorders.

One of the unique features of DMAC2 is its ability to interact with the neurotransmitter dopamine. Dopamine is a chemical that is involved in the transmission of signals in the brain and is thought to play a role in the development of many neurological disorders, including Alzheimer's disease.

Research has shown that DMAC2 is involved in the regulation of dopamine release and that it may be a useful drug target for the treatment of neurological disorders. One of the ways that DMAC2 is thought to work is by regulating the release of dopamine from the neurotransmitter-stimulated vesicles (NSVs) in the axon terminal of neurons.

NSVs are specialized structures that are present in the axon terminal of neurons and are responsible for the release of neurotransmitters, including dopamine. The release of dopamine from NSVs is regulated by a number of factors, including the neurotransmitter itself, the strength of the neurotransmitter release, and the presence of other proteins.

DMAC2 is thought to be involved in the regulation of dopamine release byNSVs by several mechanisms. First, it appears to interact with the neurotransmitter itself to regulate its release. This interaction may be through the use of a protein called GABA, which is known to interact with the neurotransmitter to regulate its release.

Another mechanism through which DMAC2 may be involved in the regulation of dopamine release is through its effects on the ion channels that are involved in dopamine release. These channels are known as the voltage-dependent channels and are thought to play a role in the regulation of dopamine release.

DMAC2 is also thought to be involved in the regulation of dopamine release byNSVs through its effects on the trafficking of dopamine release. This means that it may be involved in the movement of dopamine from the axon terminal to the dendrites of the neurons.

In addition to its role in the regulation of dopamine release, DMAC2 is also thought to be involved in the development and maintenance of neuronal connections. This is suggested by the fact that DMAC2 is a protein that is expressed in the brain and is involved in the development and maintenance of neuronal connections.

DMAC2 is also a potential biomarker for several neurological disorders, including Alzheimer's disease. This is because it is thought to be involved in the development and maintenance of the neurodegeneration that is observed in these disorders.

In conclusion, DMAC2 is a protein that is involved in the development and maintenance of neuronal connections and is a potential drug target for the treatment of neurological disorders. Its ability to interact with the neurotransmitter dopamine and its involvement in the regulation of dopamine release byNSVs make it a promising target for the development of new treatments for a variety of neurological disorders.

Protein Name: Distal Membrane Arm Assembly Component 2

Functions: Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I

The "DMAC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DMAC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DMAC2L | DMAP1 | DMBT1 | DMBT1L1 | DMBX1 | DMC1 | DMD | DMGDH | DMKN | DMP1 | DMPK | DMRT1 | DMRT2 | DMRT3 | DMRTA1 | DMRTA2 | DMRTB1 | DMRTC1 | DMRTC1B | DMRTC2 | DMTF1 | DMTF1-AS1 | DMTN | DMWD | DMXL1 | DMXL2 | DNA ligase | DNA Methyltransferase (DNMT) | DNA Polymerase alpha | DNA polymerase delta | DNA Polymerase epsilon | DNA Polymerase gamma | DNA Polymerase zeta Complex | DNA primase | DNA topoisomerase | DNA Topoisomerase II | DNA-Dependent Protein Kinase (DNA-PK) | DNA-Directed DNA Polymerase Complex | DNA-Directed RNA Polymerase | DNA-Directed RNA Polymerase I | DNA-Directed RNA Polymerase II | DNA-directed RNA polymerase II, core complex | DNA-directed RNA polymerase III | DNA2 | DNAAF1 | DNAAF10 | DNAAF11 | DNAAF2 | DNAAF3 | DNAAF4 | DNAAF4-CCPG1 | DNAAF5 | DNAAF6 | DNAAF8 | DNAAF9 | DNAH1 | DNAH10 | DNAH11 | DNAH12 | DNAH14 | DNAH17 | DNAH17-AS1 | DNAH2 | DNAH3 | DNAH5 | DNAH6 | DNAH7 | DNAH8 | DNAH8-AS1 | DNAH9 | DNAI1 | DNAI2 | DNAI3 | DNAI4 | DNAI7 | DNAJA1 | DNAJA1P3 | DNAJA1P4 | DNAJA1P5 | DNAJA2 | DNAJA3 | DNAJA4 | DNAJB1 | DNAJB11 | DNAJB12 | DNAJB13 | DNAJB14 | DNAJB2 | DNAJB3 | DNAJB4 | DNAJB5 | DNAJB6 | DNAJB6P1 | DNAJB7 | DNAJB8 | DNAJB8-AS1 | DNAJB9 | DNAJC1 | DNAJC10 | DNAJC11