E4F1: A Drug Target / Disease Biomarker (G1877)

Target Name: E4F1

NCBI ID: G1877

E4F1

E4F1: A Drug Target / Disease Biomarker

E4F1, also known as E4F1A, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and lungs. It is a key regulator of cell growth and differentiation, and is involved in the development and maintenance of tissues such as blood vessels, neural cells, and epithelial cells.

One of the reasons why E4F1 is of interest as a drug target is its role in the regulation of cell proliferation. E4F1 has been shown to play a negative role in the regulation of cell proliferation, by preventing the formation of new cells. This is important because uncontrolled cell growth can lead to the formation of cancerous tumors.

Another potential mechanism by which E4F1 may be used as a drug target is its role in the regulation of cell differentiation. E4F1 has been shown to play a key role in the regulation of neural cell differentiation, by ensuring that neural cells are properly structured and functional. This is important because neural cells are critical for the proper functioning of the brain and nervous system.

In addition to its role in cell proliferation and differentiation, E4F1 has also been shown to play a role in the regulation of cell adhesion. E4F1 helps to ensure that cells stick together and form tissues, which is important for the development and maintenance of tissues such as blood vessels and neural circuits.

Overall, E4F1 is a protein that has important roles in the regulation of cell growth, differentiation, and adhesion. As a result, it is a potential drug target for the development of new therapies for a variety of diseases.

Protein Name: E4F Transcription Factor 1

Functions: May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription

The "E4F1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about E4F1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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