EEF1B2P6: A Potential Drug Target and Biomarker (G647030)

Target Name: EEF1B2P6

NCBI ID: G647030

EEF1B2P6

Other Name(s): eukaryotic translation elongation factor 1 beta 2 pseudogene 6 | Eukaryotic translation elongation factor 1 beta 2 pseudogene 6

EEF1B2P6: A Potential Drug Target and Biomarker

The eukaryotic translation elongation factor 1 beta 2 pseudogene 6 (EEF1B2P6) is a non-coding RNA molecule that plays a critical role in the regulation of protein translation in eukaryotic cells. It is a key regulator of the translocation of non-proteinogenic coding regions ( NPPCRs) to the endoplasmic reticulum (ER) and is required for the survival of the cell. EEF1B2P6 functions as a negative regulator of the translation of NPPCRs by binding to specific regions of the ribosome.

Recent studies have identified EEF1B2P6 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and chronic diseases. The potential drug targets for EEF1B2P6 are based on its ability to regulate the translation of NPPCRs, which are often over-expressed or misregulated in cancer cells.

One of the main drug targets for EEF1B2P6 is the inhibition of its activity, which can be achieved by small molecule inhibitors or antibodies that specifically bind to EEF1B2P6. Such inhibitors have been shown to decrease the translation of NPPCRs, leading to a reduction in cell proliferation and the formation of tumors.

Another potential drug target for EEF1B2P6 is its role in the regulation of cellular processes, including cell growth, apoptosis, and autophagy. EEF1B2P6 has been shown to regulate the translation of proteins involved in cell growth and apoptosis, such as the translation of the oncogene PDGF -BB. Additionally, EEF1B2P6 has been shown to play a role in the regulation of autophagy, a process that is involved in the delivery of damaged or unnecessary cellular components to the cytosol for degradation.

In neurodegenerative diseases, EEF1B2P6 has been shown to be involved in the regulation of protein translation and to play a role in the development of neurodegeneration. For example, studies have shown that EEF1B2P6 is involved in the regulation of the translation of the neurodegenerative protein Road (NeuroD), which is often over-expressed in neurodegenerative diseases.

In conclusion, EEF1B2P6 is a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and chronic diseases. The inhibition of EEF1B2P6 activity has been shown to decrease the translation of NPPCRs, leading to a reduction in cell proliferation and the formation of tumors. Additionally, EEF1B2P6 has been shown to play a role in the regulation of cellular processes, including cell growth, apoptosis, and autophagy. Further research is needed to fully understand the role of EEF1B2P6 in disease and to develop effective therapies that target this potential drug target.

Protein Name: Eukaryotic Translation Elongation Factor 1 Beta 2 Pseudogene 6

The "EEF1B2P6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EEF1B2P6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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