Target Name: EDAR
NCBI ID: G10913
Review Report on EDAR Target / Biomarker Content of Review Report on EDAR Target / Biomarker
EDAR
Other Name(s): EDA-A1 receptor | ECTD10B | DL | EDA-A1R | Ectodysplasin A receptor | Downless homolog | anhidrotic ectodysplasin receptor 1 | Ectodysplasin 1, anhidrotic receptor | Ectodermal dysplasia receptor | ectodermal dysplasia receptor | Anhidrotic ectodysplasin receptor 1 | ectodysplasin A receptor | Downless (mouse) homolog | HRM1 | EDA1R | Tumor necrosis factor receptor superfamily member EDAR | Ectodysplasin-A receptor | downless homolog | hypohidrotic ectodermal dysplasia | ectodysplasin 1, anhidrotic receptor | EDAR_HUMAN | ED5 | EDA3 | ED3 | downless, mouse, homolog of | ECTD10A | ED1R

EDAR Receptor: A Potential Drug Target for Neurodegenerative Diseases

The EDAR receptor is a protein that is expressed in various tissues throughout the body. It is a member of the tyrosine kinase receptor family and is involved in the signaling pathway that regulates cell growth, differentiation, and survival. The EDAR receptor has been identified as a potential drug target and has been the focus of research in the field of neurodegenerative diseases.

EDAR Receptor Signaling

The EDAR receptor is involved in the regulation of several cellular processes that are essential for brain development and function. One of the key functions of the EDAR receptor is to regulate the growth and differentiation of neurons, which are the building blocks of the nervous system. The EDAR receptor plays a crucial role in the development and maintenance of the neuronal cell membrane structure, as well as the regulation of the release of neurotransmitters that are essential for communication between neurons.

The EDAR receptor is also involved in the regulation of the growth and survival of glial cells, which are the support cells of the nervous system. Glial cells are responsible for providing essential nutrients and oxygen to neurons and for helping to maintain the structural integrity of the nervous system. The EDAR receptor has been shown to play a role in the regulation of glial cell function, which may have implications for the treatment of neurodegenerative diseases.

EDAR Receptor-Mediated signaling

The EDAR receptor is involved in a number of signaling pathways that are essential for brain development and function. One of the key functions of the EDAR receptor is to regulate the growth and differentiation of neurons. The EDAR receptor has been shown to play a role in the regulation of neuronal cell membrane structure, as well as the regulation of the release of neurotransmitters that are essential for communication between neurons.

The EDAR receptor is also involved in the regulation of the growth and survival of glial cells. Glial cells are responsible for providing essential nutrients and oxygen to neurons and for helping to maintain the structural integrity of the nervous system. The EDAR receptor has been shown to play a role in the regulation of glial cell function, which may have implications for the treatment of neurodegenerative diseases.

Drug Targeting

The EDAR receptor is a potential drug target because of its involvement in several key cellular processes that are essential for brain development and function. The EDAR receptor has been shown to play a role in the regulation of neuronal cell membrane structure, as well as the regulation of the release of neurotransmitters that are essential for communication between neurons.

In addition, the EDAR receptor is involved in the regulation of the growth and survival of glial cells, which are support cells of the nervous system. The EDAR receptor has been shown to play a role in the regulation of glial cell function, which may have implications for the treatment of neurodegenerative diseases.

Conclusion

The EDAR receptor is a protein that is involved in several key cellular processes that are essential for brain development and function. The EDAR receptor has been identified as a potential drug target due to its involvement in the regulation of neuronal cell membrane structure, the regulation of neurotransmitter release, and the regulation of glial cell function. Further research is needed to fully understand the role of the EDAR receptor in neurodegenerative diseases and to develop effective treatments.

Protein Name: Ectodysplasin A Receptor

Functions: Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death

The "EDAR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EDAR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

EDARADD | EDC3 | EDC4 | EDDM3A | EDDM3B | EDEM1 | EDEM2 | EDEM3 | EDF1 | EDIL3 | EDIL3-DT | EDN1 | EDN2 | EDN3 | EDNRA | EDNRB | EDNRB-AS1 | EDRF1 | EDRF1-AS1 | EDRF1-DT | EEA1 | EED | EEF1A1 | EEF1A1P11 | EEF1A1P14 | EEF1A1P19 | EEF1A1P22 | EEF1A1P25 | EEF1A1P28 | EEF1A1P3 | EEF1A1P30 | EEF1A1P38 | EEF1A1P44 | EEF1A1P47 | EEF1A1P5 | EEF1A1P6 | EEF1A1P9 | EEF1A2 | EEF1AKMT1 | EEF1AKMT2 | EEF1AKMT3 | EEF1AKMT4 | EEF1B2 | EEF1B2P1 | EEF1B2P3 | EEF1B2P5 | EEF1B2P6 | EEF1D | EEF1DP1 | EEF1DP3 | EEF1E1 | EEF1E1-BLOC1S5 | EEF1G | EEF1GP2 | EEF1GP8 | EEF2 | EEF2K | EEF2KMT | EEFSEC | EEIG1 | EEIG2 | EEPD1 | EFCAB10 | EFCAB11 | EFCAB12 | EFCAB13 | EFCAB13-DT | EFCAB14 | EFCAB2 | EFCAB3 | EFCAB5 | EFCAB6 | EFCAB6-AS1 | EFCAB7 | EFCAB8 | EFCAB9 | EFCC1 | EFEMP1 | EFEMP2 | EFHB | EFHC1 | EFHC2 | EFHD1 | EFHD2 | EFL1 | EFL1P1 | EFNA1 | EFNA2 | EFNA3 | EFNA4 | EFNA5 | EFNB1 | EFNB2 | EFNB3 | EFR3A | EFR3B | EFS | EFTUD2 | EGF | EGFEM1P