Target Name: ECEL1
NCBI ID: G9427
Review Report on ECEL1 Target / Biomarker Content of Review Report on ECEL1 Target / Biomarker
ECEL1
Other Name(s): Endothelin-converting enzyme-like 1 (isoform 1) | DA5D | ECEL1 variant 1 | Endothelin-converting enzyme-like 1 | endothelin converting enzyme like 1 | damage induced neuronal endopeptidase | X converting enzyme | Xce protein | Endothelin converting enzyme like 1, transcript variant 1 | XCE | ECEX | ECEL1_HUMAN | DINE

ECEL1: A Potential Drug Target and Biomarker

Endothelin-converting enzyme-like 1 (ISOFORM 1) is a protein that is expressed in various tissues throughout the body, including the heart, lungs, kidneys, and liver. It plays a critical role in the regulation of blood pressure, as it helps to remove excess fluid from the body by increasing the production of urine.

Recent studies have suggested that ECEL1 may have potential as a drug target or biomarker. In this article, we will explore the biology and potential clinical applications of ECEL1, as well as the research that has been done to investigate its potential as a drug.

The biology of ECEL1

ECEL1 is a 23-kDa protein that is expressed in a variety of tissues throughout the body. It is highly conserved across different species, which suggests that it has a important role in the evolution of the human species. ECEL1 is primarily localized to the cytoplasm of cells, where it is involved in the regulation of various physiological processes.

One of the key functions of ECEL1 is its role in the regulation of sodium and water balance. ECEL1 is involved in the production of urine, which helps to remove excess fluid from the body. It does this by increasing the production of urine and by decreasing the amount of sodium and water that is reabsorbed from the blood by the kidneys. This helps to maintain a healthy balance of fluids in the body and, in doing so, keeps the pressure on the blood vessels that supply the body's tissues.

In addition to its role in fluid regulation, ECEL1 is also involved in the regulation of cell signaling pathways. It is a potent inhibitor of the angiotensin-converting enzyme (ACE), which is a key enzyme involved in the regulation of blood pressure. ECEL1 has been shown to inhibit the activity ofACE and to reduce the production of angiotensin II, which is a potent vasoconstrictor.

Potential clinical applications of ECEL1

The potential clinical applications of ECEL1 are vast, as it has been shown to have a wide range of effects in various physiological processes. The most promising potential applications of ECEL1 as a drug target or biomarker are its potential to treat hypertension and heart failure.

Hypertension, or high blood pressure, is a serious health condition that affects millions of people worldwide. It is a leading cause of cardiovascular disease, including heart attack, stroke, and heart failure. ECEL1 has been shown to be involved in the regulation of blood pressure and has been shown to have potential as a drug target for hypertension. Several studies have shown that ECEL1 inhibitors can significantly reduce blood pressure in individuals with hypertension.

Heart failure is a serious condition that can be caused by a variety of factors, including heart muscle damage or problems with the heart's electrical system. It is a leading cause of morbidity and mortality in older adults and has a poor prognosis. ECEL1 has been shown to be involved in the regulation of heart function and has been shown to have potential as a drug target for heart failure. Several studies have shown that ECEL1 inhibitors can improve heart function in individuals with heart failure.

In addition to its potential to treat hypertension and heart failure, ECEL1 has also been shown to have potential as a biomarker for these conditions. Blood pressure and heart function are critical markers of overall health, and ECEL1 has been shown to be involved in the regulation of these processes. Using ECEL1 as a biomarker for hypertension and heart failure could be a valuable tool for the diagnosis and treatment of these conditions.

The research on ECEL1

Several studies have been conducted to investigate the biology and potential clinical applications of ECEL1. These studies have provided valuable insights into the role of ECEL1 in various physiological processes and have identified several potential drug targets.

One of the most significant findings of these studies is the role of ECEL1 in the regulation of sodium and water balance. As mentioned earlier, ECEL1 is involved in the production of urine and in the regulation of sodium and water balance. Studies have shown that ECEL1 inhibits the activity of

Protein Name: Endothelin Converting Enzyme Like 1

Functions: May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides

The "ECEL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ECEL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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