Target Name: EDF1
NCBI ID: G8721
Review Report on EDF1 Target / Biomarker Content of Review Report on EDF1 Target / Biomarker
EDF1
Other Name(s): Multiprotein-bridging factor 1 | multiprotein bridging factor 1 | Endothelial differentiation-related factor 1 (isoform alpha) | endothelial differentiation related factor 1 | OTTHUMP00000022617 | OTTHUMP00000022616 | EDF-1 | MGC9058 | Multiprotein bridging factor 1 | MBF1 | EDF1_HUMAN | Multiprotein bridging factor-1 | CFAP280 | EDF1 variant alpha | Endothelial differentiation-related factor 1 | Endothelial differentiation related factor 1, transcript variant alpha

EDF1: Key Regulator of Cell-Cell Adhesion and Potential Drug Targets

EDF1 (Multiprotein-bridging factor 1) is a protein that plays a critical role in the development and maintenance of tissues and organs, including blood vessels, neurons, and muscles. It is a key regulator of cell-cell adhesion, which is a process that ensures the integrity of tissues and is critical for various physiological functions. EDF1 has also been shown to be involved in a variety of signaling pathways, including the regulation of cell growth, differentiation, and survival.

Despite its importance, little is known about EDF1 and its potential drug targets or biomarkers. In this article, we will explore the role of EDF1 in cell-cell adhesion and its potential as a drug target.

The Importance of Cell-Cell Adhesion

Cell-cell adhesion is the process by which cells stick together to form tissues and organs. This process is critical for the development and maintenance of tissues and is involved in many physiological functions, including embryonic development, tissue repair, and regeneration.

EDF1 is a key regulator of cell-cell adhesion. It is a protein that plays a critical role in the formation of tight junctions, which are the protein channels that allow cells to stick together and form tight junctions. These connections are critical for the proper functioning of tissues and are involved in various physiological functions, including the regulation of ion and solute transport, as well as the regulation of cell signaling pathways.

In addition to its role in cell-cell adhesion, EDF1 has also been shown to be involved in a variety of signaling pathways. For example, it has been shown to be involved in the regulation of cell growth, differentiation, and survival. has also been shown to play a role in the regulation of cell-cell signaling pathways, including the regulation of cell-cell adhesion, angiogenesis, and vascular remodeling.

Potential Drug Targets

The potential use of EDF1 as a drug target is due to its involvement in various signaling pathways and its role in the regulation of cell-cell adhesion. There are several potential drug targets that have been identified that are involved in these signaling pathways, including the regulation of cell-cell adhesion.

One potential drug target for EDF1 is the inhibitor of the protein N-cadherin. N-cadherin is a protein that is involved in cell-cell adhesion and has been shown to play a role in the regulation of various physiological functions, including the regulation of cell growth, differentiation, and survival. Interactions between N-cadherin and EDF1 have been identified, and it is possible that inhibitors of N-cadherin could be useful in targeting EDF1.

Another potential drug target for EDF1 is the tyrosine kinase FAK. FAK is a protein that is involved in various signaling pathways, including the regulation of cell-cell adhesion. Interactions between FAK and EDF1 have been identified, and it is possible that inhibitors of FAK could be useful in targeting EDF1.

Biomarkers

EDF1 has also been shown to be involved in the regulation of various physiological functions, including the regulation of cell-cell adhesion. There are several potential biomarkers that could be used to assess the activity of EDF1, including the expression of EDF1 in various tissues and cells, the formation of tight junctions, and the regulation of cell-cell adhesion.

One potential biomarker for EDF1 is the expression of EDF1 in various tissues and cells. EDF1 is a protein that is expressed in a variety of tissues and cells, including blood vessels, neurons, and muscles. The expression of EDF1 in these tissues and cells can be used as a

Protein Name: Endothelial Differentiation Related Factor 1

Functions: Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism

The "EDF1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EDF1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

EDIL3 | EDIL3-DT | EDN1 | EDN2 | EDN3 | EDNRA | EDNRB | EDNRB-AS1 | EDRF1 | EDRF1-AS1 | EDRF1-DT | EEA1 | EED | EEF1A1 | EEF1A1P11 | EEF1A1P14 | EEF1A1P19 | EEF1A1P22 | EEF1A1P25 | EEF1A1P28 | EEF1A1P3 | EEF1A1P30 | EEF1A1P38 | EEF1A1P44 | EEF1A1P47 | EEF1A1P5 | EEF1A1P6 | EEF1A1P9 | EEF1A2 | EEF1AKMT1 | EEF1AKMT2 | EEF1AKMT3 | EEF1AKMT4 | EEF1B2 | EEF1B2P1 | EEF1B2P3 | EEF1B2P5 | EEF1B2P6 | EEF1D | EEF1DP1 | EEF1DP3 | EEF1E1 | EEF1E1-BLOC1S5 | EEF1G | EEF1GP2 | EEF1GP8 | EEF2 | EEF2K | EEF2KMT | EEFSEC | EEIG1 | EEIG2 | EEPD1 | EFCAB10 | EFCAB11 | EFCAB12 | EFCAB13 | EFCAB13-DT | EFCAB14 | EFCAB2 | EFCAB3 | EFCAB5 | EFCAB6 | EFCAB6-AS1 | EFCAB7 | EFCAB8 | EFCAB9 | EFCC1 | EFEMP1 | EFEMP2 | EFHB | EFHC1 | EFHC2 | EFHD1 | EFHD2 | EFL1 | EFL1P1 | EFNA1 | EFNA2 | EFNA3 | EFNA4 | EFNA5 | EFNB1 | EFNB2 | EFNB3 | EFR3A | EFR3B | EFS | EFTUD2 | EGF | EGFEM1P | EGFL6 | EGFL7 | EGFL8 | EGFLAM | EGFR | EGFR-AS1 | EGLN1 | EGLN2 | EGLN3