Target Name: TSPAN15
NCBI ID: G23555
Review Report on TSPAN15 Target / Biomarker Content of Review Report on TSPAN15 Target / Biomarker
TSPAN15
Other Name(s): 2700063A19Rik | tspan-15 | NET-7 | Tetraspanin-15 (isoform 1) | TSN15_HUMAN | Tetraspanin 15, transcript variant 1 | Tetraspan NET-7 | NET7 | tetraspanin-15 | Transmembrane 4 superfamily member 15 | transmembrane 4 superfamily member tetraspan NET-7 | transmembrane 4 superfamily member 15 | Tspan-15 | TM4SF15 | Tetraspanin-15 | tetraspan NET-7 | TSPAN15 variant 1 | tetraspanin 15

Exploring the Potential Drug Target TSPAN15 (2700063A19Rik)

TSPAN15 (2700063A19Rik), a gene located on chromosome 6, has been identified as a potential drug target in the field of neurodegenerative diseases. This gene has been associated with various neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. It is also known to play a role in the development of neurodegeneration in various diseases, including neurofibrillary tangles and neuroglial plaques.

The search for potential drug targets has become a significant focus in the pharmaceutical industry in recent years. Drug targets are identified by researchers using various techniques, such as gene expression analysis, RNA interference, and biochemical assays. Once a potential drug target is identified, further studies are conducted to determine its functional role in disease and to develop potential therapeutic strategies.

TSPAN15: A Potential Drug Target

TSPAN15 has been shown to be involved in various neurological disorders. It has been linked to the development of neurodegeneration, neurofibrillary tangles, and neuroglial plaques, which are hallmarks of neurodegenerative diseases. The study of TSPAN15 has also shown that it is involved in the regulation of neurotransmitter release, which is critical for proper brain function.

In addition to its association with neurodegeneration, TSPAN15 has also been shown to play a role in the development of various neurological disorders. For example, TSPAN15 has been linked to the development of Alzheimer's disease, as well as the development of Parkinson's disease, Huntington's disease, and other neurodegenerative disorders.

The Potential Benefits of Targeting TSPAN15

Targeting TSPAN15 as a drug target has the potential to treat a variety of neurological disorders. If TSPAN15 is found to be involved in the development and progression of neurodegenerative diseases, targeting this gene could provide new therapeutic strategies for treating these disorders.

One potential approach to targeting TSPAN15 is through the use of small molecules or antibodies that can interact with the gene and prevent its translation into protein. This would result in a reduction in the levels of TSPAN15 protein and potentially slow down or reverse the progression of neurodegeneration.

Another potential approach to targeting TSPAN15 is through the use of drugs that can modulate its expression levels. This could involve using drugs that inhibit the activity of enzymes involved in TSPAN15 synthesis, or drugs that increase the levels of TSPAN15 RNA.

The Potential Risks of Targeting TSPAN15

Targeting TSPAN15 as a drug target also has the potential to pose some risks. One of the main risks is that it may have unforeseen effects on other genes or molecules in the body. For example, the use of drugs that modulate TSPAN15 expression levels may also affect the expression of other genes involved in neurodegeneration.

Another potential risk of targeting TSPAN15 is that it may not be a reliable drug target. While TSPAN15 has been shown to be involved in the development and progression of neurodegenerative diseases, further studies are needed to determine its role in these diseases and to develop effective therapeutic strategies.

Conclusion

TSPAN15 is a gene that has been associated with various neurological disorders. Further studies are needed to determine its role in the development and progression of neurodegenerative diseases and to develop effective therapeutic strategies. If TSPAN15 is found to be involved in the development and progression of these diseases, targeting this gene with drugs or other therapeutic approaches could provide new and effective treatments for a variety of neurological disorders.

Protein Name: Tetraspanin 15

Functions: Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862, PubMed:30463011). Promotes ADAM10-mediated cleavage of CDH2 (By similarity). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862)

The "TSPAN15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TSPAN15 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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TSPAN16 | TSPAN17 | TSPAN18 | TSPAN19 | TSPAN2 | TSPAN3 | TSPAN31 | TSPAN32 | TSPAN33 | TSPAN4 | TSPAN5 | TSPAN6 | TSPAN7 | TSPAN8 | TSPAN9 | TSPEAR | TSPEAR-AS1 | TSPEAR-AS2 | TSPO | TSPO2 | TSPOAP1 | TSPOAP1-AS1 | TSPY1 | TSPY2 | TSPY26P | TSPY3 | TSPY4 | TSPYL1 | TSPYL2 | TSPYL4 | TSPYL5 | TSPYL6 | TSR1 | TSR2 | TSR3 | TSSC2 | TSSC4 | TSSK1B | TSSK2 | TSSK3 | TSSK4 | TSSK6 | TST | TSTD1 | TSTD2 | TSTD3 | TTBK1 | TTBK2 | TTC1 | TTC12 | TTC13 | TTC14 | TTC16 | TTC17 | TTC19 | TTC21A | TTC21B | TTC21B-AS1 | TTC22 | TTC23 | TTC23L | TTC24 | TTC26 | TTC27 | TTC28 | TTC28-AS1 | TTC29 | TTC3 | TTC3-AS1 | TTC30A | TTC30B | TTC31 | TTC32 | TTC33 | TTC34 | TTC36 | TTC38 | TTC39A | TTC39A-AS1 | TTC39B | TTC39C | TTC39C-AS1 | TTC3P1 | TTC4 | TTC41P | TTC5 | TTC6 | TTC7A | TTC7B | TTC8 | TTC9 | TTC9-DT | TTC9B | TTC9C | TTF1 | TTF2 | TTI1 | TTI2 | TTK | TTL