Target Name: TSSK4
NCBI ID: G283629
Review Report on TSSK4 Target / Biomarker Content of Review Report on TSSK4 Target / Biomarker
TSSK4
Other Name(s): TSSK4_HUMAN | Serine/threonine kinase 22E | TSSK5 | STK22E | Testis-specific serine/threonine-protein kinase 4 (isoform 1) | TSK4 | C14orf20 | testis specific serine kinase 4 | TSSK-4 | Serine/threonine-protein kinase 22E | Testis-specific serine/threonine-protein kinase 4 | TSK-4 | Testis specific serine kinase 4, transcript variant 1 | Testis-specific kinase 4 | Testis-specific serine kinase 4 | serine/threonine kinase 22E | serine/threonine-protein kinase 22E | TSSK4 variant 1

TSSK4: A Potential Drug Target for Cancer and Other Diseases

TSSK4 (TSSK4_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the Tsk gene family, which encodes a protein involved in cell signaling pathways. TSSK4 has been shown to play a role in the regulation of cellular processes such as cell adhesion, migration, and invasion.

One of the unique features of TSSK4 is its ability to interact with several different proteins, including F-actinin and N-cadherin. This interaction between TSSK4 and these proteins makes it a potential drug target for various diseases.

In cancer, TSSK4 has been shown to be involved in the development and progression of several types of cancer, including breast, ovarian, and prostate cancer. For example, studies have shown that high levels of TSSK4 expression are associated with poor prognosis in breast cancer patients. Additionally, TSSK4 has been shown to promote the growth and survival of cancer cells in cell culture, which could make it a useful biomarker for tracking the effectiveness of cancer treatments.

In addition to its role in cancer, TSSK4 has also been shown to be involved in the regulation of cellular processes that are important for normal development and function. For example, TSSK4 has been shown to play a role in the regulation of cell division and the assembly of tissues. It has also been shown to interact with proteins involved in the development and maintenance of the nervous system, including the protein T-cell factor (TGF-β).

TSSK4 has also been shown to play a role in the regulation of the immune system. Studies have shown that TSSK4 interacts with the protein PDGF-尾, which is involved in the regulation of cell growth and differentiation. This interaction between TSSK4 and PDGF-尾 could make TSSK4 a potential drug target for diseases that are characterized by uncontrolled cell growth, such as cancer.

In conclusion, TSSK4 is a protein that has been shown to play a role in a variety of cellular processes that are important for normal development and function. Its ability to interact with multiple proteins makes it a potential drug target for various diseases, including cancer. Further research is needed to fully understand the role of TSSK4 in cellular processes and its potential as a drug target.

Protein Name: Testis Specific Serine Kinase 4

Functions: Serine/threonine kinase which is involved in male germ cell development and in mature sperm function (By similarity). May be involved in the Cre/Creb signaling pathway (By similarity). Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells (PubMed:15964553). Phosphorylates CREM on 'Ser-116' in vitro (By similarity). Phosphorylates ODF2 on 'Ser-95' (By similarity)

The "TSSK4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TSSK4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TSSK6 | TST | TSTD1 | TSTD2 | TSTD3 | TTBK1 | TTBK2 | TTC1 | TTC12 | TTC13 | TTC14 | TTC16 | TTC17 | TTC19 | TTC21A | TTC21B | TTC21B-AS1 | TTC22 | TTC23 | TTC23L | TTC24 | TTC26 | TTC27 | TTC28 | TTC28-AS1 | TTC29 | TTC3 | TTC3-AS1 | TTC30A | TTC30B | TTC31 | TTC32 | TTC33 | TTC34 | TTC36 | TTC38 | TTC39A | TTC39A-AS1 | TTC39B | TTC39C | TTC39C-AS1 | TTC3P1 | TTC4 | TTC41P | TTC5 | TTC6 | TTC7A | TTC7B | TTC8 | TTC9 | TTC9-DT | TTC9B | TTC9C | TTF1 | TTF2 | TTI1 | TTI2 | TTK | TTL | TTLL1 | TTLL1-AS1 | TTLL10 | TTLL11 | TTLL12 | TTLL13 | TTLL2 | TTLL3 | TTLL4 | TTLL5 | TTLL6 | TTLL7 | TTLL8 | TTLL9 | TTN | TTN-AS1 | TTPA | TTPAL | TTR | TTT Complex | TTTY1 | TTTY10 | TTTY11 | TTTY13 | TTTY14 | TTTY15 | TTTY16 | TTTY17A | TTTY17B | TTTY19 | TTTY2 | TTTY20 | TTTY21 | TTTY22 | TTTY4B | TTTY4C | TTTY5 | TTTY6 | TTTY7 | TTTY8 | TTTY9A