TSPY26P: A Potential Drug Target and Biomarker for Testis-Specific Protein Y-linked 26

Target Name: TSPY26P

NCBI ID: G128854

TSPY26P

Other Name(s): testis specific protein Y-linked 26, pseudogene | Testis specific protein Y-linked 26, pseudogene | TSPYL3 | bA392M18.1

TSPY26P: A Potential Drug Target and Biomarker for Testis-Specific Protein Y-linked 26

Introduction

Testis-specific protein Y-linked 26 (TSPY26P) is a protein that plays a crucial role in the development and maintenance of testicular tissue. TSPY26P is a member of the Y-linked translocation protein family, which plays important roles in spermatogenesis, embryonic development and Play a key role in reproductive tract development. However, TSPY26P is only expressed in Leydig cells under normal circumstances, which limits its role in studying male reproductive system diseases.

In recent years, researchers have found that TSPY26P is expressed in a variety of cancers, such as testicular cancer, prostate cancer, and lung cancer. In addition, TSPY26P is also closely related to the occurrence and development of various diseases, such as spermatogenesis disorders, abnormal embryonic development and male immune system disorders. Therefore, TSPY26P is regarded as a potential drug target and biomarker.

Function and biology of TSPY26P

TSPY26P is a translocation protein of the non-homologous segment of the ZW chromosome, and its encoding gene is located on the X chromosome. TSPY26P consists of two subunits: 伪 subunit and 尾 subunit. Each subunit contains a Y-linked translocation sequence, which is composed of a specific DNA-binding protein (DNBP) and a transcription factor-binding protein (TBP).

The role of TSPY26P in spermatogenesis and embryonic development

TSPY26P plays an important role in spermatogenesis. During spermatogenesis, the TSPY26P伪 subunit interacts with DNBP and TBP to promote the binding of DNBP to chromatin, thereby changing the chromatin structure and providing necessary conditions for spermatogenesis. In addition, TSPY26P is also closely related to several key steps in spermatogenesis, such as meiosis, chromosome structure remodeling, and post-meiotic maturation.

The role of TSPY26P in embryonic development and reproductive tract development

During embryonic development, the TSPY26P伪 subunit interacts with DNBP and TBP and participates in the differentiation and development of germ cells. In addition, the TSPY26P尾 subunit plays a role in the development and morphological maintenance of the embryonic cyst cavity and is related to the immune response of the embryo.

The relationship between TSPY26P and diseases

TSPY26P is expressed in a variety of cancers, such as testicular cancer, prostate cancer, and lung cancer. Studies have found that TSPY26P expression levels are positively correlated with the prognosis of various cancers. In addition, TSPY26P is also closely related to the occurrence and development of various diseases, such as spermatogenesis disorders, abnormal embryonic development and male immune system disorders.

The significance of TSPY26P as a drug target and biomarker

TSPY26P has high potential as a drug target. TSPY26P is expressed in a variety of cancers, therefore, intervention targeting TSPY26P may have positive implications for the treatment of these diseases. Currently, several studies are exploring TSPY26P as a drug target for cancer treatment.

TSPY26P also has high value as a biomarker. TSPY26P is expressed in a variety of cancers. Therefore, by detecting the expression level of TSPY26P, early diagnosis, monitoring and prognosis assessment of the disease can be carried out. In addition, the expression level of TSPY26P is also related to spermatogenesis and embryonic development.

Protein Name: Testis Specific Protein Y-linked 26, Pseudogene

The "TSPY26P Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TSPY26P comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets