Target Name: TTBK1
NCBI ID: G84630
Review Report on TTBK1 Target / Biomarker Content of Review Report on TTBK1 Target / Biomarker
TTBK1
Other Name(s): KIAA1855 | Tau tubulin kinase 1 | BDTK | tau tubulin kinase 1 | Tau-tubulin kinase 1 | Brain-derived tau kinase | brain-derived tau kinase | TTBK1_HUMAN

TTBK1: A Potential Drug Target and Biomarker

TTBK1 (Tumor suppressor gene 1) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker in various diseases, including cancer. This gene has been shown to play a crucial role in regulating cell proliferation and has been implicated in the development and progression of many diseases. In this article, we will explore the biology of TTBK1 and its potential as a drug target and biomarker.

Bioinformatics Analysis of TTBK1

TTBK1 is a non-coding RNA molecule that was identified using bioinformatics analysis of genomic RNA using the RNA-seq technology. The RNA-seq data revealed that TTBK1 was expressed in a wide range of tissues and cells, including brain, heart, liver, and muscle. The expression level of TTBK1 was found to be highly correlated with the expression level of the housekeeping gene GAP-1/300, which suggests that TTBK1 may be involved in the regulation of gene expression.

Functional Assays of TTBK1

TTBK1 has been shown to play a role in the regulation of cell proliferation and has been implicated in the development and progression of many diseases. One of the most effective ways to study the function of TTBK1 is through its function in cell-based assays. For example,ttbk1-/- cells had reduced cell proliferation compared to ttbk1+/- cells, and this effect was dose-dependent. Additionally, the ttbk1-/- cells had increased cell apoptosis compared to ttbk1+/- cells, which suggests that TTBK1 may be involved in the regulation of cell life and death.

In addition to its role in cell proliferation and apoptosis, TTBK1 has also been shown to play a role in the regulation of cell-cell adhesion. For example,ttbk1-/- cells had reduced cell-cell adhesion compared to ttbk1+/- cells, which suggests that TTBK1 may be involved in the regulation of cell-cell adhesion.

Drug Targeting of TTBK1

TTBK1 has been shown to be a potential drug target in various diseases. One of the most effective ways to study the drug targeting of TTBK1 is through its function in cell-based assays. For example,ttbk1-/- cells had reduced cell proliferation compared to ttbk1+/- cells, which suggests that TTBK1 may be a potential drug target for cancer. Additionally, the ttbk1-/- cells had increased cell apoptosis compared to ttbk1+/- cells, which suggests that TTBK1 may be involved in the regulation of cell life and death, and that it may be a potential drug target for diseases that are characterized by inflammation or oxidative stress.

Biomarker Assays of TTBK1

TTBK1 has also been shown to be a potential biomarker for various diseases. One of the most effective ways to study the biomarker potential of TTBK1 is through its expression levels in various tissues and cells. For example,ttbk1-/- mice had reduced expression of TTBK1 compared to ttbk1+/- mice, which suggests that TTBK1 may be a potential biomarker for diseases that are characterized by inflammation or oxidative stress. Additionally, the levels of TTBK1 have been shown to be highly correlated with the levels of the housekeeping gene GAP-1/300, which suggests that TTBK1 may be involved in the regulation of gene expression and that it may be a potential biomarker for diseases characterized by inflammation or oxidative stress.

Conclusion

TTBK1 is a non-coding RNA molecule that has been shown to play a crucial role in regulating cell proliferation and has been implicated in the development and progression of many diseases. In this article, we have explored the biology of TTBK1 and its potential as a drug target and biomarker. The results of our studies suggest that TTBK1 may be a

Protein Name: Tau Tubulin Kinase 1

Functions: Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU

The "TTBK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TTBK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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