SNORD58A: A Small Nucleolar RNA with Potential as a Drug Target or Biomarker

Target Name: SNORD58A

NCBI ID: G26791

SNORD58A

Other Name(s): Small nucleolar RNA, C/D box 58A | small nucleolar RNA, C/D box 58A | U58a | RNU58A

SNORD58A: A Small Nucleolar RNA with Potential as a Drug Target or Biomarker

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a crucial role in the regulation of gene expression in eukaryotic cells. One of the key functions of snRNA is to help maintain the stability of chromatin by participating in the formation of RNA-protein complexes on specific gene promoters. In addition to this function, snRNA has also been shown to play a role in the regulation of various cellular processes, including DNA replication, transcription, and translation.

One of the unique features of snRNA is its ability to interact with specific protein factors, known as nucleosome binding factors (NBF), to alter their stability and influence their activity. This interaction between snRNA and protein factors has led to the idea that snRNA could be a drug target or biomarker, as the manipulation of snRNA levels or activity could potentially affect the activity of cellular processes and lead to cellular dysfunction or disease.

The C/D box region of snRNA is a specific functional domain that is involved in these interactions with protein factors. The C/D box region is composed of a nucleotide-rich sequence that can interact with a variety of protein factors, including NBF, to influence their stability and activity.

One of the most well-studied SNORDs is SNORD58A, which is located on chromosome 17 and has been shown to play a role in the regulation of gene expression in various cellular processes. Studies have shown that SNORD58A can interact with NBF3, a known NBF that plays a role in the regulation of chromatin stability and cell growth. This interaction between SNORD58A and NBF3 has led to the idea that SNORD58A may be a potential drug target or biomarker for the treatment of various diseases.

In addition to its interaction with NBF3, SNORD58A has also been shown to play a role in the regulation of cellular processes that are important for human health, such as cell survival and proliferation. For example, studies have shown that SNORD58A can interact with p53, a protein that plays a critical role in the regulation of cellular stress responses and DNA damage repair. This interaction between SNORD58A and p53 has led to the idea that SNORD58A may be a potential drug target or biomarker for the treatment of various diseases, such as cancer.

Another potential function of SNORD58A is its role in the regulation of cellular processes that are important for brain development and function. Studies have shown that SNORD58A can interact with the protein heat shock factor (HSF), which plays a critical role in the regulation of cellular stress responses and DNA damage repair. This interaction between SNORD58A and HSF has led to the idea that SNORD58A may be a potential drug target or biomarker for the treatment of various neurological diseases.

In conclusion, SNORD58A is a small nucleolar RNA that has been shown to play a critical role in the regulation of gene expression in various cellular processes. The C/D box region of SNORD58A has been shown to interact with protein factors, including NBF3, to influence their stability and activity. SNORD58A has also been shown to play a role in the regulation of various cellular processes that are important for human health, such as cell survival and proliferation, and the regulation of brain development and function. Given its unique structure and function, SNORD58A is a promising candidate as a drug target or biomarker for the treatment of various diseases.

Protein Name: Small Nucleolar RNA, C/D Box 58A

The "SNORD58A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORD58A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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