Target Name: SNU13
NCBI ID: G4809
Review Report on SNU13 Target / Biomarker Content of Review Report on SNU13 Target / Biomarker
SNU13
Other Name(s): non-histone chromosome protein 2-like 1 | OTK27 | High mobility group-like nuclear protein 2 homolog 1 | hSNU13 | SNU13 variant 1 | NHP2L1 | Non-histone chromosome protein 2 (S. cerevisiae)-like 1 | Small nuclear ribonucleoprotein 13, transcript variant 1 | SPAG12 | small nuclear ribonucleoprotein 13 | U4/U6.U5 small nuclear ribonucleoprotein SNU13 | U4/U6.U5 tri-snRNP 15.5 kDa protein | FA1 | SNRNP15-5 | NHP2 non-histone chromosome protein 2-like 1 | [U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein | FA-1 | NHP2-like protein 1, N-terminally processed | 15.5K | SSFA1 | SNU13 homolog | SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) | NHP2-like protein 1 | NH2L1_HUMAN | sperm specific antigen 1 | NHPX | high mobility group-like nuclear protein 2 homolog 1

SNU13: A Non-Histone Chromosome Protein 2-Like 1 as a Potential Drug Target and Biomarker

Chromosomes are essential components of the nucleus of a cell, responsible for the storage of genetic information. Chromosomes consist of two main types: histones and non-histone proteins. Histones are small, positively charged proteins that play a critical role in the organization and regulation of DNA during the cell cycle. On the other hand, non-histone proteins are large, complex molecules that have various functions in regulating gene expression, DNA replication, and repair, and other cellular processes.

SNU13 is a non-histone chromosome protein 2-like 1, which means it is a protein that belongs to the group of non-histone proteins and is similar to the protein 2-like 1. SNU13 is a 14 kDa protein that is expressed in various tissues and cells, including muscle, heart, kidney, liver, and brain. It is involved in various cellular processes, including cell signaling, DNA replication, and repair, and is considered as a potential drug target and biomarker.

Drug Target Potential

SNU13 has been identified as a potential drug target due to its unique structure and various functions. One of the key reasons for its potential as a drug target is its unique structure. SNU13 has a distinct N-terminus, a unique C-terminus, and a variable R-terminus. This unique structure allows for the development of specific drugs that can interact with SNU13 and modulate its function. Additionally, SNU13 has multiple potential drug targets, including those involved in cell signaling, DNA replication, and repair.

Biomarker Potential

SNU13 has the potential to serve as a biomarker for various diseases, including cancer. Its involvement in cell signaling, DNA replication, and repair makes it an attractive target for cancer therapies. For instance, SNU13 has been shown to be involved in the regulation of cell proliferation, which is a critical step in the development of cancer. Additionally, SNU13 has been shown to play a role in the regulation of cell apoptosis, which is a natural mechanism that helps the body eliminate damaged or dysfunctional cells.

Conclusion

SNU13 is a non-histone chromosome protein 2-like 1 that has various functions in regulating gene expression, DNA replication, and repair. Its unique structure and multiple potential drug targets make it an attractive target for drug development. Additionally, SNU13 has the potential to serve as a biomarker for various diseases, including cancer. Further research is needed to fully understand the role of SNU13 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Small Nuclear Ribonucleoprotein 13

Functions: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28781166). Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed:10545122, PubMed:17412961). The protein undergoes a conformational change upon RNA-binding (PubMed:17412961, PubMed:10545122, PubMed:28781166)

The "SNU13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNU13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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