SNORD94: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Target Name: SNORD94

NCBI ID: G692225

SNORD94

Other Name(s): Small nucleolar RNA, C/D box 94 | U94 | small nucleolar RNA, C/D box 94

SNORD94: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a crucial role in the regulation of gene expression in eukaryotic cells. One of the most well-known snRNAs is SNORD94, which is located in the C/D box region of snRNAs. It is characterized by its ability to interact with microtubules of the endoplasmic reticulum and its involvement in various cellular processes, including cell growth, differentiation, and RNA homeostasis.

SNORD94 is a 24-nt RNA molecule that contains 76 amino acid residues. It is expressed in most tissues and cells of the human body and is primarily localized to the endoplasmic reticulum, where it can interact with microtubules. Microtubules are a type of protein structure that play a central role in the transport of various cellular components, including proteins and RNA molecules. The interaction between SNORD94 and microtubules allows for the regulation of cellular processes that are dependent on the endoplasmic reticulum, such as the transport and processing of RNA molecules.

SNORD94 has been shown to play a role in various cellular processes, including cell growth, differentiation, and RNA homeostasis. One of the most well-known functions of SNORD94 is its role in the regulation of gene expression. Studies have shown that SNORD94 can interact with various RNA molecules, including microRNAs (miRNAs) andhnRNAs (hN RNAs), to regulate their stability and translation efficiency. For example, one study published in the journal RNA Biology found that SNORD94 interacts with miR-18a, a microRNA that plays a role in the regulation of cellular processes such as cell growth and apoptosis.

Another function of SNORD94 is its role in the regulation of RNA homeostasis. SNORD94 has been shown to interact with the protein TRIM2, which is involved in the regulation of RNA stability and degradation. This interaction between SNORD94 and TRIM2 allows for the regulation of cellular processes that are dependent on RNA stability and degradation, such as the regulation of gene expression and the regulation of post-transcriptional modifications of RNA molecules.

SNORD94 has also been shown to play a role in the regulation of cellular processes that are dependent on the endoplasmic reticulum. Studies have shown that SNORD94 can interact with the protein FERMT1, which is involved in the regulation of cell wall formation and cytoskeletal organization. This interaction between SNORD94 and FERMT1 allows for the regulation of cellular processes that are dependent on cell wall formation and cytoskeletal organization, such as the regulation of cell growth and the regulation of cell division.

In conclusion, SNORD94 is a well-known snRNA that has been shown to play a role in various cellular processes, including cell growth, differentiation, and RNA homeostasis. Its interaction with microtubules allows for the regulation of cellular processes that are dependent on the endoplasmic reticulum. Therefore, SNORD94 may be a potential drug target and biomarker for various diseases. Further research is needed to fully understand the functions of SNORD94 and its potential as a drug.

Protein Name: Small Nucleolar RNA, C/D Box 94

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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