SNORD47: A Potential Drug Target and Biomarker (G26802)

Target Name: SNORD47

NCBI ID: G26802

SNORD47

Other Name(s): small nucleolar RNA, C/D box 47 | U47 | Small nucleolar RNA, C/D box 47 | RNU47

SNORD47: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA) is a class of non-coding RNAs that play critical roles in various cellular processes, including chromatin regulation, gene expression, and stress response. One of the most well-known snRNAs is SNORD47, which is located within the C/D box region of RNA molecules. Although the primary function of SNORD47 is not well understood, its potential involvement in various cellular processes has led to its potential as a drug target or biomarker.

The C/D box region of RNA molecules is a conserved domain that is present in various snRNAs, including SNORD47. This region plays a crucial role in the stability and localization of snRNAs, and is involved in their interactions with protein factors. The C/D box region is also known for its ability to form base-pairing bonds with other RNA molecules, which may influence the stability and function of these molecules.

One of the key features of SNORD47 is its ability to form base-pairing bonds with other snRNAs, including the well-known protein splicer RNA (SPRNA). This interaction between SNORD47 and SPRNA suggests that it may play a role in regulating splicing, a critical process that is involved in the production of functional RNA molecules from DNA templates.

In addition to its potential role in splicing regulation, SNORD47 has also been shown to be involved in the regulation of gene expression. Studies have shown that SNORD47 can interact with various RNA molecules, including spliced RNA, to prevent their translation into protein products. This interaction between SNORD47 and RNA molecules suggests that it may play a role in the regulation of gene expression.

The potential drug target status of SNORD47 is further supported by its expression in various tissues and organisms, including human tissues. Studies have shown that SNORD47 is expressed in a variety of tissues, including brain, heart, and muscle. Additionally, the expression of SNORD47 has been shown to be regulated by various factors, including cellular stress, suggesting that it may play a role in the regulation of cellular stress responses.

The potential use of SNORD47 as a drug target is further enhanced by its known interactivity with the protein kinase A-type ubiquitin protein (UBP). UBP is a well-known protein that is involved in a variety of cellular processes, including DNA damage repair, gene expression, and cell signaling. Studies have shown that UBP can interact with various RNA molecules, including SNORD47. This interaction between UBP and SNORD47 suggests that SNORD47 may be a potential target for UBP-based therapeutics.

In conclusion, SNORD47 is a well-known snRNA that is involved in various cellular processes. Its expression and interaction with other RNA molecules suggests that it may be a potential drug target or biomarker. Further studies are needed to fully understand the role of SNORD47 in cellular processes and its potential as a drug target.

Protein Name: Small Nucleolar RNA, C/D Box 47

The "SNORD47 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORD47 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets