Target Name: SDCBP2
NCBI ID: G27111
Review Report on SDCBP2 Target / Biomarker Content of Review Report on SDCBP2 Target / Biomarker
SDCBP2
Other Name(s): ST-2 | Syntenin-2 (isoform a) | SITAC18 | syndecan binding protein (syntenin) 2 | Syndecan binding protein 2, transcript variant 1 | SITAC | Syntenin-2 (isoform Alpha) | Similar to TACIP18 | ST2 | Syntenin-2 | SDCBP2 variant 1 | SDCB2_HUMAN | Syndecan-binding protein 2 | syndecan binding protein 2

SDCBP2: A Potential Drug Target for Various Diseases

SDCBP2 (Sterile Developmental Component-B2) is a protein that is expressed in various tissues of the body, including the brain, spleen, and thymus. It is a member of the CDK4 complex, which is a group of proteins that are involved in cell growth and development.

Recent studies have identified SDCBP2 as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because SDCBP2 has been shown to play a role in the development and progression of these diseases, and in some cases, its levels have been found to be elevated in the affected tissues.

One of the key reasons for the potential of SDCBP2 as a drug target is its involvement in the regulation of cell growth and differentiation. Studies have shown that SDCBP2 plays a role in the control of cell proliferation and in the regulation of cell-cell adhesion. This is important because these processes are critical for the development and maintenance of tissues and organs, and are often disrupted in diseases such as cancer and neurodegenerative diseases.

In addition to its role in cell growth and differentiation, SDCBP2 has also been shown to be involved in the regulation of cell survival. Studies have shown that SDCBP2 can protect cells from apoptosis, which is a process by which cells are intentionally or unintentionally destroyed. This is important because cells that are able to survive and divide are more likely to contribute to the growth and maintenance of tissues and organs, while cells that are destroyed or undergo programmed cell death are not.

Another potential mechanism by which SDCBP2 may contribute to the development and progression of diseases is its role in the regulation of the immune system. Studies have shown that SDCBP2 is involved in the development and regulation of natural killer cells, which are a type of immune cell that play an important role in detecting and destroying infected or abnormal cells in the body.

In addition to its potential role in the regulation of cell growth, differentiation, and survival, SDCBP2 has also been shown to be involved in the regulation of cell-cell interactions and the development of tissues. For example, studies have shown that SDCBP2 plays a role in the development of the blood-brain barrier, which is a barrier that separates the brain from the surrounding blood vessels and is important for the exchange of nutrients and oxygen to the brain.

Given the potential involvement of SDCBP2 in the regulation of cell growth, differentiation, and survival, as well as its involvement in the regulation of the immune system and the development of tissues, it is possible that SDCBP2 could be a useful drug target for the treatment of various diseases. For example, studies have shown that SDCBP2 has been shown to be involved in the development and progression of cancer, and that its levels have been found to be elevated in various tissues of the body. This suggests that SDCBP2 may be a useful target for the treatment of cancer.

In addition to its potential role in cancer, SDCBP2 has also been shown to be involved in the treatment of neurodegenerative diseases. For example, studies have shown that SDCBP2 has been shown to play a role in the development and progression of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. This suggests that SDCBP2 may be a useful target for the treatment of neurodegenerative diseases.

Finally, SDCBP2 has also been shown to be involved in the treatment of autoimmune disorders. For example, studies have shown that SDCBP2 has been shown to play a role in the development and progression of autoimmune disorders such as rheumatoid arthritis and Crohn's disease. This suggests that SDCBP2 may be a useful target for the treatment of autoimmune disorders.

In conclusion, SDCBP2 is a protein that is involved in the regulation of cell growth and differentiation, as well as the regulation of cell survival and the development of tissues. Its potential as a drug target for the treatment of various diseases makes it an attractive target for further research. Further studies are needed to fully understand the role of SDCBP2 in the development and progression of diseases, as well as its potential as a drug.

Protein Name: Syndecan Binding Protein 2

Functions: Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed:15961997)

The "SDCBP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SDCBP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SDCBP2-AS1 | SDCBPP2 | SDCCAG8 | SDE2 | SDF2 | SDF2L1 | SDF4 | SDHA | SDHAF1 | SDHAF2 | SDHAF3 | SDHAF4 | SDHAP1 | SDHAP2 | SDHAP3 | SDHAP4 | SDHB | SDHC | SDHD | SDHDP1 | SDHDP2 | SDK1 | SDK1-AS1 | SDK2 | SDR16C5 | SDR16C6P | SDR39U1 | SDR42E1 | SDR42E2 | SDR9C7 | SDS | SDSL | SEBOX | SEC11A | SEC11B | SEC11C | SEC13 | SEC14L1 | SEC14L1P1 | SEC14L2 | SEC14L3 | SEC14L4 | SEC14L5 | SEC14L6 | SEC16A | SEC16B | SEC1P | SEC22A | SEC22B | SEC22C | SEC23A | SEC23B | SEC23IP | SEC24A | SEC24AP1 | SEC24B | SEC24B-AS1 | SEC24C | SEC24D | SEC31A | SEC31B | SEC61A1 | SEC61A2 | SEC61B | SEC61G | SEC62 | SEC63 | SEC63P2 | SECISBP2 | SECISBP2L | SECTM1 | Segment polarity protein dishevelled homolog | SEH1L | SEL1L | SEL1L2 | SEL1L3 | SELE | SELENBP1 | SELENOF | SELENOH | SELENOI | SELENOK | SELENOKP1 | SELENOM | SELENON | SELENOO | SELENOOLP | SELENOP | Selenoprotein | SELENOS | SELENOT | SELENOV | SELENOW | SELL | SELP | SELPLG | SEM1 | SEM1P1 | SEMA3A | SEMA3B