SNAI3: A Potential Drug Target and Biomarker for Snails (G333929)

Target Name: SNAI3

NCBI ID: G333929

SNAI3

SNAI3: A Potential Drug Target and Biomarker for Snails

Snails, known for their slow-moving pace and love for snails, have long been a fascinating subject in the scientific community. These creatures have a unique way of interacting with their environment, and their behavior has been the subject of extensive research. In recent years, scientists have been interested in investigating the snail family Zinc Finger 3 (SNAI3) as a potential drug target and biomarker.

The SNAI3 gene

SNAI3 is a gene that is located on the X chromosome and encodes for a zinc finger protein. Zinc finger proteins are a family of transmembrane proteins that play a crucial role in various cellular processes. They are characterized by a conserved N-terminal zinc finger motif and a C-terminal domain that contains a variety of functionalities. SNAI3 is a member of the SNAI family, which includes several similar genes, including SNAI1, SNAI2, and SNAI4.

SNAI3 function

SNAI3 is involved in various cellular processes that are important for the development and maintenance of tissues. One of its well-known functions is in cell signaling. SNAI3 has been shown to play a role in the regulation of cell proliferation, differentiation, and survival.

SNAI3 has been shown to promote the growth and survival of various cell types, including cancer cells. It has also been shown to inhibit the growth and survival of normal cell types, which may have implications for the development of cancer.

SNAI3 as a drug target

SNAI3 has been identified as a potential drug target due to its involvement in cell signaling and its ability to promote cancer growth. Researchers have shown that inhibiting SNAI3 function can lead to a variety of therapeutic effects, including the inhibition of cancer cell growth, cell death, and angiogenesis.

One of the compounds that has been shown to inhibit SNAI3 function is a drug called PF-1012, which is a small molecule that blocks the activity of SNAI3. PF-1012 has been shown to be effective in preclinical studies for the treatment of various cancers, including breast, ovarian, and colorectal cancers.

SNAI3 as a biomarker

SNAI3 has also been identified as a potential biomarker for cancer. The expression of SNAI3 has been shown to be elevated in various types of cancer, including breast, ovarian, and colorectal cancers. This suggests that SNAI3 may be a useful biomarker for the diagnosis and monitoring of these cancers.

SNAI3 has also been shown to be downregulated in various cancer-related tissues, including cancer cells, normal tissues, and cancer-infiltrated tissues. This suggests that SNAI3 may be a useful target for cancer therapies that target the regulation of SNAI3 function.

Conclusion

SNAI3 is a gene that has been shown to play a crucial role in various cellular processes, including cell signaling and cancer development. As a potential drug target and biomarker, SNAI3 has the potential to revolutionize our understanding of cancer biology and treatment. Further research is needed to fully understand the functions of SNAI3 and its potential as a drug and biomarker.

Protein Name: Snail Family Transcriptional Repressor 3

Functions: Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3' (By similarity)

The "SNAI3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNAI3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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