SNHG14: A Potential Drug Target and Biomarker for Inflammatory Neurodegenerative Diseases

Target Name: SNHG14

NCBI ID: G104472715

SNHG14

SNHG14: A Potential Drug Target and Biomarker for Inflammatory Neurodegenerative Diseases

Introduction

Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and multiple sclerosis, are one of the main causes of disability in the elderly and disabled people. These diseases often result in neuronal loss and disruption of neural circuits, leading to symptoms such as cognitive impairment, movement disorders, and pain. Currently, although there are no specific drugs that can cure these diseases, some drugs can slow the progression of the disease and improve patients' quality of life. Therefore, research on new drug targets and biomarkers is an important direction in the treatment of these diseases.

SNHG14 is a gene found to be associated with neuron loss and disruption of neural circuits in the nervous system. Abnormal expression of SNHG14 has been confirmed in multiple neurodegenerative diseases. Decreased expression levels and dysfunction of the SNHG14 gene may lead to neuronal damage and death, thereby aggravating the development of these diseases.

drug target

SNHG14 is a potential drug target because it is a key factor in neuronal damage and neural circuit disruption. Research shows that SNHG14 can affect neurons in multiple ways, including regulating neuronal survival, synaptic plasticity, and neuronal connections.

First, SNHG14 can regulate neuronal survival. Neuronal death is caused by multiple factors, including oxidative stress, inflammation, and neurotoxins. Studies have shown that SNHG14 can inhibit neuronal apoptosis, thereby extending the life of neurons.

Secondly, SNHG14 can affect synaptic plasticity. Synaptic plasticity refers to the plasticity and adjustability of synaptic connections between neurons. Research shows that SNHG14 can affect synaptic plasticity and the connections between neurons, thereby affecting the transmission of information between neurons.

Finally, SNHG14 can affect the connections between neurons. The connections between neurons are a key factor in neuron function, allowing them to interact and transmit information. Research shows that SNHG14 can affect the connections between neurons, thereby affecting the transmission of information between neurons.

Biomarkers

SNHG14 is a potential biomarker that can be used to detect neuronal damage and neural circuit disruption. Some studies have shown that the expression level of SNHG14 can reflect the degree of neuronal damage and the degree of neural circuit disruption. In addition, SNHG14 can also be used to detect neuronal death because its expression level decreases with neuronal death.

in conclusion

SNHG14 is a potential drug target that can be used to treat neurodegenerative diseases. By regulating neuronal survival, synaptic plasticity, and connections between neurons, SNHG14 can affect neuronal function and thereby improve the treatment of neurodegenerative diseases. In addition, SNHG14 can also be used to detect neuronal damage and neural circuit destruction, providing an important theoretical basis for the research and treatment of neurodegenerative diseases.

Protein Name: Small Nucleolar RNA Host Gene 14

The "SNHG14 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNHG14 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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