Target Name: IGBP1
NCBI ID: G3476
Review Report on IGBP1 Target / Biomarker Content of Review Report on IGBP1 Target / Biomarker
IGBP1
Other Name(s): ALPHA-4 | renal carcinoma antigen NY-REN-16 | CD79a-binding protein 1 | Renal carcinoma antigen NY-REN-16 | immunoglobulin binding protein 1 | bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ) | OTTHUMP00000023464 | IGBP1_HUMAN | Protein phosphatase 2/4/6 regulatory subunit | Protein phosphatase 2A, regulatory subunit alpha-4 | IGBP1 variant 1 | B-cell signal transduction molecule alpha 4 | IBP1 | immunoglobulin (CD79A) binding protein 1 | protein alpha-4 | OTTHUMP00000023465 | BA351K23.1 (immunoglobulin binding protein 1 (CD79A) ) | alpha4 | B cell signal transduction molecule alpha 4 | Immunoglobulin binding protein 1, transcript variant 1 | Immunoglobulin-binding protein 1 | protein phosphatase 2/4/6 regulatory subunit | MRXS28 | Protein alpha-4 | protein phosphatase 2A, regulatory subunit alpha-4 | Immunoglobulin-binding protein 1 (isoform 1)

Unlocking the Potential of IGBP1 (ALPHA-4) as a Drug Target and Biomarker

Introduction

The Interleukin-纬 (IL-纬) signaling pathway has become an increasingly fascinating research focus in recent years due to its involvement in various physiological processes and its role in the immune response.IL-纬 is a cytokine that plays a crucial role in the regulation of immune and inflammatory responses. It is involved in the regulation of cellular processes such as cell adhesion, survival, and cytokine production. One of the most important functions of IL-纬 is its ability to induce the recruitment of immune cells to the site of an infection or injury, thereby contributing to the immune response.

IGBP1 (ALPHA-4), a 21-kDa protein, has been identified as a potential drug target and biomarker in various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. IGBP1 is a key component of the IL-纬 signaling pathway and has been shown to play a critical role in the regulation of cellular processes, including inflammation, cell adhesion, and survival.

The IGBP1 Signaling Pathway

The IGBP1 protein is a key component of the IL-纬 signaling pathway, which is a complex regulatory network that plays a crucial role in the regulation of cellular processes, including inflammation, cell adhesion, and survival. The IGBP1 protein is involved in the regulation of the activity of several key transcription factors, including nuclear factor kappa B (NF-kappa-B), transcription factor-DNA binding protein (TPP) and cytokine interleukin-1 (IL-1), etc. These transcription factors play an important role in regulating inflammatory responses, immune cell recruitment, cell proliferation and inducing apoptosis in cells.

The relationship between IGBP1 and diseases

Many diseases, including cancer, cardiovascular disease, and neurodegenerative diseases, are closely related to dysregulation of the IL-纬 signaling pathway. The key to treating these diseases lies in accurately regulating the IL-纬 signaling pathway to inhibit adverse processes such as inflammatory response, immune cell recruitment, and cell proliferation.

As a potential drug target, IGBP1 provides scientists with an attractive target. Intervention by targeting IGBP1 could potentially treat many diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

The potential of IGBP1 as a biomarker

The role of IGBP1 in tumors, cardiovascular and neurodegenerative diseases also suggests that it may have potential as a biomarker. By measuring IGBP1 levels in the blood, disease progression and treatment response can be predicted. In addition, IGBP1 may also be used as an indicator for evaluating the efficacy of therapeutic drugs.

Research methods

Currently, researchers are exploring the application of IGBP1 in drug research and clinical treatment. In order to verify the potential of IGBP1 as a drug target, the researchers used a variety of experimental methods, including Western blotting, DNA-fragmentation assay, fluorescence quantitative PCR, cell culture and in vivo experiments. These experimental results indicate that IGBP1 has a significant role in inducing apoptosis and recruiting immune cells in a variety of tumors, cardiovascular diseases, and neurodegenerative diseases.

Conclusion

IGBP1 is one of thousands of proteins with significant potential as a drug target. Its impact on the IL-纬 signaling pathway and its potential application as a biomarker in disease diagnosis and treatment make IGBP1 an attractive research topic. With the continuous advancement of technology, future research will continue to deeply explore the application of IGBP1 in drug research and clinical treatment, bringing more hope to human health.

Protein Name: Immunoglobulin Binding Protein 1

Functions: Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits

The "IGBP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IGBP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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