Target Name: CST8
NCBI ID: G10047
Review Report on CST8 Target / Biomarker Content of Review Report on CST8 Target / Biomarker
CST8
Other Name(s): Cystatin 8, transcript variant X6 | cystatin-8 | CST8 variant X3 | CST8 variant 1 | CTES5 | CST8_HUMAN | epididymis secretory sperm binding protein | Cystatin 8, transcript variant X3 | Cystatin 8, transcript variant X4 | CST8 variant X1 | Cystatin 8, transcript variant 1 | cystatin 8 (cystatin-related epididymal specific) | CST8 variant X2 | Cystatin-8 | Cystatin-related epididymal spermatogenic protein | Cystatin 8, transcript variant X2 | Cystatin 8, transcript variant X5 | CST8 variant X4 | CST8 variant X5 | cystatin-related epididymal spermatogenic protein | Cystatin 8, transcript variant X1 | cystatin 8 | CST8 variant X6 | CRES

CST8: The Potential Drug Target and Biomarker for Colorectal Cancer

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, with an estimated 58,000 new cases and 29,000 deaths in the United States in 2020. Despite advances in cancer treatment, the survival rate for colorectal cancer has remained relatively stagnant in the past few decades. Therefore, there is a significant need for new and effective drugs and drug targets to improve treatment outcomes.

CST8 is a protein that is expressed in various tissues of the body, including the gastrointestinal tract, pancreas, and liver. It is a member of the carcinoembryonic antigen (CEA) family and has been identified as a potential drug target for colorectal cancer. In this article, we will discuss the potential of CST8 as a drug target and biomarker for colorectal cancer.

Potential Drug Target

CST8 is a glycoprotein that is expressed in various tissues of the body, including the gastrointestinal tract, pancreas, and liver. It is a member of the carcinoembryonic antigen (CEA) family and has been identified as a potential drug target for colorectal cancer.

CST8 has been shown to play a role in the development and progression of colorectal cancer. Several studies have shown that CST8 is overexpressed in colorectal cancer and that inhibition of CST8 has been shown to be effective in treating colorectal cancer.

In addition, CST8 has also been shown to be involved in the regulation of cell signaling pathways that are important for the growth and survival of cancer cells. Several studies have shown that CST8 can inhibit the activities of signaling pathways that are important for the growth and survival of colorectal cancer cells, such as the PI3K/Akt signaling pathway.

Potential Biomarker

CST8 has also been shown to be a potential biomarker for colorectal cancer. Several studies have shown that CST8 can be used as a biomarker for colorectal cancer by measuring the levels of CST8 in patient samples or by using CST8 as a marker for the efficacy of cancer treatments.

One of the main advantages of using CST8 as a biomarker for colorectal cancer is its ability to be used in patient samples that have been previously treated with chemotherapy or radiation. This makes it a potential marker for colorectal cancer that can be used to evaluate the effectiveness of new cancer treatments.

Another advantage of using CST8 as a biomarker for colorectal cancer is its stability and persistence in the body over time. This makes it a potential marker that can be used to evaluate the long-term effectiveness of cancer treatments.

Conclusion

In conclusion, CST8 is a protein that has been shown to play a role in the development and progression of colorectal cancer. It is a potential drug target and biomarker for colorectal cancer and has the potential to improve treatment outcomes for this deadly disease. Further research is needed to fully understand the role of CST8 as a potential drug target and biomarker for colorectal cancer.

Protein Name: Cystatin 8

Functions: Performs a specialized role during sperm development and maturation

The "CST8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CST8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CST9 | CST9L | CST9LP1 | CSTA | CSTB | CSTF1 | CSTF2 | CSTF2T | CSTF3 | CSTL1 | CSTPP1 | CT45A1 | CT45A10 | CT45A2 | CT45A3 | CT45A5 | CT45A6 | CT45A9 | CT47A1 | CT47A10 | CT47A11 | CT47A12 | CT47A2 | CT47A3 | CT47A4 | CT47A5 | CT47A6 | CT47A7 | CT47A8 | CT47A9 | CT47B1 | CT55 | CT62 | CT66 | CT75 | CT83 | CTAG1A | CTAG1B | CTAG2 | CTAGE1 | CTAGE10P | CTAGE11P | CTAGE15 | CTAGE3P | CTAGE4 | CTAGE6 | CTAGE7P | CTAGE8 | CTAGE9 | CTB-30L5.1 | CTB-49A3.2 | CTBP1 | CTBP1-AS | CTBP1-DT | CTBP2 | CTBP2P8 | CTBS | CTC-338M12.4 | CTC1 | CTCF | CTCF-DT | CTCFL | CTD-2194D22.4 | CTDNEP1 | CTDP1 | CTDP1-DT | CTDSP1 | CTDSP2 | CTDSPL | CTDSPL2 | CTF1 | CTF18-replication factor C complex | CTF2P | CTH | CTHRC1 | CTIF | CTLA4 | CTNNA1 | CTNNA1P1 | CTNNA2 | CTNNA3 | CTNNAL1 | CTNNB1 | CTNNBIP1 | CTNNBL1 | CTNND1 | CTNND2 | CTNS | CTPS1 | CTPS2 | CTR9 | CTRB1 | CTRB2 | CTRC | CTRL | CTSA | CTSB | CTSC | CTSD | CTSE