MIR7-1: A Potential Drug Target and Biomarker for Various Diseases
MIR7-1: A Potential Drug Target and Biomarker for Various Diseases
MIR7-1 (hsa-miR-7-5p), a microRNA (miRNA), is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. MIR7-1 is a highly conserved miRNA that is expressed in various tissues and cell types, including the brain, heart, and gastrointestinal tract.
The miRNA system is a small non-coding RNA molecule that plays a critical role in post-transcriptional gene regulation. MiRNAs are designed to target specific mRNAs for degradation, and their levels can be regulated by various factors, including target mRNA stability, local interactions , and interactions with factors such as RNA-binding protein (RBP), which plays a crucial role in the stability of pre-mRNA.
MIR7-1 is a highly conserved miRNA that is expressed in various tissues and cell types, including the brain, heart, and gastrointestinal tract. It is characterized by a unique structure, consisting of a hairpin-like domain and a single open-ended tail . The miRNA is approximately 20-22 nucleotides in length and has a typical exonic sequence of AUGGUGUGAAGAAGAA.
MIR7-1 has been shown to play a critical role in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. For example, MIR7-1 has been shown to promote the growth of cancer cells and to contribute to their survival. It has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells commit suicide to eliminate themselves when they are no longer needed.
In addition to its role in cell survival and apoptosis, MIR7-1 has also been shown to play a critical role in transcriptional regulation. It has been shown to interact with various RNA-binding proteins (RBP), including CBP, which is a well- known regulator of microRNA stability. By interacting with CBP, MIR7-1 has been shown to enhance the stability of its target mRNAs and to play a role in their translation into protein.
MIR7-1 has also been shown to play a role in the regulation of cellular processes that are important for overall health and wellbeing, including inflammation and stress resistance. For example, MIR7-1 has been shown to be involved in the regulation of the production of pro-inflammatory cytokines, such as TNF-alpha, by promoting the translation of its target genes into protein.
In conclusion, MIR7-1 is a highly conserved and non-coding miRNA that has been shown to play a critical role in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. Its unique structure and conserved sequence make it an attractive target for further research and potential therapeutic applications. Further studies are needed to fully understand the mechanisms of MIR7-1's role in cellular processes and its potential as a drug target or biomarker.
Protein Name: MicroRNA 7-1
The "MIR7-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR7-1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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