PCDH8_HUMAN: A Protein of Interest for Drug Development and Cancer Research

Target Name: PCDH8

NCBI ID: G5100

PCDH8

PCDH8_HUMAN: A Protein of Interest for Drug Development and Cancer Research

PCDH8 (Peroxisome Driven Controlled Gene 8) is a gene that encodes a protein known as PCDH8_HUMAN. PCDH8_HUMAN is a protein that is expressed in various tissues of the body, including the brain, heart, and lungs. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells.

PCDH8_HUMAN is unique among its kind because it is expressed in only one cell type: the placenta. The placenta is a specialized tissue that plays a critical role in the development and maintenance of fetal tissue in the womb. It is the site where all of the nutrients and oxygen needed by the baby are transferred from the mother to the baby, and it is also the site where many of the hormones and waste products produced by the body are eliminated.

The expression of PCDH8_HUMAN in the placenta is of particular interest from a drug development perspective because it allows researchers to study the effects of drugs on placenta function. This is important because the placenta plays a critical role in the development and health of the fetus, and drugs that affect placenta function can have serious consequences for the baby.

PCDH8_HUMAN is also of interest as a potential biomarker for various diseases, including cancer. Because it is expressed in only one cell type, it is a reliable and robust marker for the presence of certain proteins in cancer cells. This makes it an attractive target for cancer therapies that are designed to target specific proteins.

In addition to its potential drug-targeting properties, PCDH8_HUMAN is also of interest to researchers because of its unique structure and function. PCDH8_HUMAN is a member of the superfamily of cytoskeletal proteins, which are characterized by the presence of a protein called alpha-helices. These protein molecules are responsible for the structure and stability of the cytoskeleton, and they are involved in many important cellular processes, including cell division, migration, and mechanical forces.

The structure and function of PCDH8_HUMAN are also of interest because they are closely linked to the development and progression of cancer. Many studies have suggested that changes in the expression of PCDH8_HUMAN are associated with the development and progression of cancer. For example, PCDH8_HUMAN has been shown to be expressed in various types of cancer, including breast, lung, and ovarian cancer. This suggests that it may be a useful biomarker for these diseases.

In conclusion, PCDH8_HUMAN is a protein that is of interest to researchers due to its unique structure and function. Its expression in the placenta makes it a reliable and robust marker for the presence of certain proteins in cancer cells, and its expression in various types of cancer makes it a potential biomarker for these diseases. Additionally, its structure and function are closely linked to the development and progression of cancer, making it an attractive target for drug development.

Protein Name: Protocadherin 8

Functions: Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity)

The "PCDH8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PCDH8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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