Target Name: PCF11
NCBI ID: G51585
Review Report on PCF11 Target / Biomarker Content of Review Report on PCF11 Target / Biomarker
PCF11
Other Name(s): PCF11 cleavage and polyadenylation factor subunit | PCF11 variant 3 | Pre-mRNA cleavage complex 2 protein Pcf11 (isoform 3) | PCF11, cleavage and polyadenylation factor II subunit, homolog | Pcf11 | PCF11 cleavage and polyadenylation factor subunit, transcript variant 3 | Pre-mRNA cleavage complex II protein Pcf11 | PCF11_HUMAN | pre-mRNA cleavage complex II protein Pcf11 | KIAA0824 | PCF11p homolog | PCF11, cleavage and polyadenylation factor subunit, homolog | Pre-mRNA cleavage complex 2 protein Pcf11

PCF11's Role in Disease and Condition Management

Proteins play a crucial role in every cell of the body. They are the building blocks of life, and they perform a wide range of functions. One of the important proteins is PCF11 (polyadenylate regulatory factor 11), which is a subunit of the polyadenylate regulatory factor 11 (PRF11) gene. PCF11 is a protein that is expressed in many different tissues and cells of the body. Its primary function is to regulate the activity of PRF11, which is a protein that is involved in the regulation of DNA replication and transcription.

Diseases and conditions that are associated with PCF11 dysfunction

PCF11 is involved in many different processes in the body, and it is often involved in the development and progression of diseases and conditions. One of the most well-known is cancer. PCF11 has been shown to be involved in the regulation of cell cycle progression , which is a critical step in the development and progression of cancer.

PCF11 is often used as a drug target or biomarker in cancer treatment. Doctors and researchers have shown that inhibiting PCF11 activity can lead to the inhibition of cancer cell growth and the regression of cancer tumors. This is because PCF11 is involved in the regulation of cell cycle progression, which is a critical step in the development and progression of cancer.

Another disorder that is associated with PCF11 dysfunction is neurodegenerative diseases. These conditions include Alzheimer's disease, Parkinson's disease, and Huntington's disease. Studies have shown that PCF11 gene dysfunction is associated with increased levels of oxidative stress in neurodegenerative diseases. The function of PCF11 in neurons and its correlation with neurodegenerative diseases provide new ideas for studying the pathogenesis of these diseases and developing treatments.

Additionally, PCF11 has been linked to many other diseases and conditions. For example, the role of PCF11 in liver disease has been extensively studied. Research shows that PCF11 is dysregulated in liver disease and may lead to liver damage and fibrosis.

Pharmacology and clinical applications of PCF11

PCF11 has great potential in drug discovery and research. Because PCF11 is expressed in many different tissues and cells, it is an excellent drug target. Currently, there are many studies devoted to inhibiting the activity of PCF11 to treat various diseases.

In cancer treatment, PCF11 inhibitors have made some progress. Studies have shown that inhibiting PCF11 activity can significantly inhibit the growth and proliferation of cancer cells. In addition, PCF11 inhibitors can also inhibit the apoptosis of tumor cells and improve the survival rate of tumor treatment. Therefore, PCF11 inhibitor is a promising cancer treatment drug.

In the treatment of neurodegenerative diseases, PCF11 also

Protein Name: PCF11 Cleavage And Polyadenylation Factor Subunit

Functions: Component of pre-mRNA cleavage complex II

The "PCF11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PCF11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PCF11-AS1 | PCGEM1 | PCGF1 | PCGF2 | PCGF3 | PCGF3-AS1 | PCGF5 | PCGF6 | PCID2 | PCIF1 | PCK1 | PCK2 | PCLAF | PCLO | PCM1 | PCMT1 | PCMTD1 | PCMTD1-DT | PCMTD2 | PCNA | PCNA-AS1 | PCNAP1 | PCNAP3 | PCNP | PCNPP1 | PCNT | PCNX1 | PCNX2 | PCNX3 | PCNX4 | PCOLCE | PCOLCE-AS1 | PCOLCE2 | PCOTH | PCP2 | PCP4 | PCP4L1 | PCSK1 | PCSK1N | PCSK2 | PCSK4 | PCSK5 | PCSK6 | PCSK6-AS1 | PCSK7 | PCSK9 | PCTP | PCYOX1 | PCYOX1L | PCYT1A | PCYT1B | PCYT2 | PDAP1 | PDC | PDCD1 | PDCD10 | PDCD11 | PDCD1LG2 | PDCD2 | PDCD2L | PDCD4 | PDCD4-AS1 | PDCD5 | PDCD6 | PDCD6IP | PDCD6IPP2 | PDCD6P1 | PDCD7 | PDCL | PDCL2 | PDCL3 | PDCL3P4 | PDCL3P6 | PDE10A | PDE11A | PDE11A-AS1 | PDE12 | PDE1A | PDE1B | PDE1C | PDE2A | PDE2A-AS1 | PDE3A | PDE3B | PDE4A | PDE4B | PDE4C | PDE4D | PDE4DIP | PDE5A | PDE6A | PDE6B | PDE6C | PDE6D | PDE6G | PDE6H | PDE7A | PDE7B | PDE7B-AS1 | PDE8A