PCOLCE-AS1: A Potential Drug Target and Biomarker (G100129845)

Target Name: PCOLCE-AS1

NCBI ID: G100129845

PCOLCE-AS1

Other Name(s): PCOLCE antisense RNA 1

PCOLCE-AS1: A Potential Drug Target and Biomarker

Post-translational modification (PTM) of proteins is a process that involves the addition, removal, or modification of functional groups such as phosphate or acetyl groups. These modifications play a crucial role in the regulation of protein function and are involved in various cellular processes, including cell signaling, protein-protein interactions, and intracellular signaling pathways. One of the well-known post-translational modifications is protein-associated post-translational modifications (PA-PTMs), which are modifications that occur on the protein after translation but before it becomes functional.

PA-PTMs have been implicated in a wide range of cellular processes, including cell signaling, stress response, and protein-protein interactions. Many of these modifications have been linked to the regulation of protein stability, localization, and interactions with other proteins. In recent years, there has been growing interest in the use of small molecules as inhibitors of PA-PTMs to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the protein post-translational modifications that has received a lot of attention in recent years is PCOLCE-AS1. PCOLCE-AS1 is a protein that is expressed in various tissues and cells, including the brain, heart, and gastrointestinal tract. It is involved in the regulation of cellular processes, including cell signaling, cell division, and cell survival.

The PCOLCE-AS1 gene

The PCOLCE-AS1 gene is located on chromosome 12q34 and encodes a protein that is composed of 1,214 amino acids. The protein has a molecular weight of 19.9 kDa and a calculated pI of 5.6. It is expressed in various tissues and cells, including the brain, heart, and gastrointestinal tract.

The PCOLCE-AS1 protein

PCOLCE-AS1 is a member of the A-type protein kinase (ATP-kinase) family, which is a subfamily of the protein kinase superfamily. ATP-kinases are a group of proteins that are involved in the regulation of cellular processes, including cell signaling, protein-protein interactions, and intracellular signaling pathways.

PCOLCE-AS1 is involved in the regulation of cellular processes, including cell signaling, cell division, and cell survival. It is involved in the formation of the endoplasmic reticulum (ER), which is the protein synthesis and quality control system in the cell. It is also involved in the regulation of the cytoskeleton, which is the structure that organizes the cell's cytoplasm.

PCOLCE-AS1 functions as an ATP-kinase

PCOLCE-AS1 functions as an ATP-kinase, which is a protein that is involved in the regulation of cellular processes, including cell signaling, protein-protein interactions, and intracellular signaling pathways. ATP-kinases are a group of proteins that are involved in the regulation of cellular processes, including the formation of the endoplasmic reticulum (ER), the regulation of protein synthesis and degradation, and the regulation of intracellular signaling pathways.

PCOLCE-AS1 is involved in the regulation of cellular processes, including cell signaling, cell division, and cell survival. It is involved in the formation of the endoplasmic reticulum (ER), which is the protein synthesis and quality control system in the cell. It is also involved in the regulation of the cytoskeleton, which is the structure that organizes the cell's cytoplasm.

PCOLCE-AS1 is a potential drug target

PCOLCE-AS1 is a potential drug target because of its involvement in cellular processes, including cell signaling, cell division, and cell survival. It is also involved in the regulation of protein synthesis and degradation, which are crucial for the development and progression of diseases.

In addition, PCOLCE-AS1 is a protein that is expressed in various tissues and cells, including the brain, heart, and gastrointestinal tract. This makes it a promising target for small molecules that can inhibit its function.

Conclusion

In conclusion, PCOLCE-AS1 is a protein that is involved in the regulation of cellular processes, including cell signaling, cell division, and cell survival. It is also involved in the regulation of protein synthesis and degradation and is a potential drug target. Further research is needed to understand the full function of PCOLCE-AS1 and its potential as a drug target.

Protein Name: PCOLCE Antisense RNA 1

The "PCOLCE-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PCOLCE-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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