PCDH12: A Non-Coding RNA Molecule as A Potential Drug Target and Cancer Biomarker

Target Name: PCDH12

NCBI ID: G51294

PCDH12

PCDH12: A Non-Coding RNA Molecule as A Potential Drug Target and Cancer Biomarker

PCDH12 (Peripheral Component Data High-Density Array) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. PCDH12 is a key regulator of gene expression in the nervous system and has been involved in the development and progression of several neurological disorders.

The Importance of PCDH12

PCDH12 is a non-coding RNA molecule that plays a crucial role in the regulation of gene expression in the nervous system. It is expressed in a variety of tissues and cells throughout the body and has been implicated in the development and progression of several neurological disorders, including cancer.

PCDH12 has been shown to be involved in the regulation of neuronal differentiation and plasticity, as well as the control of synaptic plasticity. It has been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, and has also been linked to the development of certain cancers, such as neuroblastoma.

PCDH12 as a Drug Target

PCDH12 has been identified as a potential drug target due to its involvement in the regulation of gene expression and its role in the development of neurological disorders. Several studies have shown that inhibiting PCDH12 can lead to the downregulation of its target genes and the improvement of neuronal function in various neurological models, such as mouse models of Alzheimer's disease and Parkinson's disease.

In addition to its potential as a drug target, PCDH12 has also been shown to be a potential biomarker for several neurological disorders. The expression of PCDH12 has been shown to be decreased in the brains of individuals with certain neurological disorders, such as Alzheimer's disease and Parkinson's disease. This suggests that PCDH12 may be a useful biomarker for these disorders and could potentially serve as a target for new therapies.

PCDH12 as a Potential Cancer Biomarker

PCDH12 has also been shown to be involved in the regulation of cancer cell growth and progression. Several studies have shown that PCDH12 can be expressed in the brains of individuals with certain types of cancer, such as neuroblastoma, and that its expression is associated with the development of these tumors.

In addition to its potential role in cancer, PCDH12 has also been shown to be involved in the regulation of cell survival and apoptosis, which are important processes that are regulated by the expression of several other genes. The regulation of cell survival and apoptosis by PCDH12 may be a potential mechanism by which this molecule could be targeted as a cancer biomarker or drug target.

Conclusion

PCDH12 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various neurological disorders, including cancer. Its role in the regulation of gene expression and its involvement in the development and progression of neurological disorders make it an attractive target for new therapies. Additionally, PCDH12 has also been shown to be involved in the regulation of cancer cell growth and progression, which may be a potential mechanism by which this molecule could be targeted as a cancer biomarker or drug target. Further research is needed to fully understand the role of PCDH12 in these processes and to develop new treatments based on this molecule.

Protein Name: Protocadherin 12

Functions: Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions (By similarity). Acts as a regulator of cell migration, probably via increasing cell-cell adhesion (PubMed:21402705). Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions (By similarity). Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity)

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