Target Name: SAR1A
NCBI ID: G56681
Review Report on SAR1A Target / Biomarker Content of Review Report on SAR1A Target / Biomarker
SAR1A
Other Name(s): OTTHUMP00000019748 | SAR1 gene homolog A | Secretion associated Ras related GTPase 1A, transcript variant 1 | SAR1 | Sara | OTTHUMP00000019743 | SAR1a gene homolog 1 | GTP-binding protein SAR1a | secretion associated Ras related GTPase 1A | SAR1A variant 1 | SAR1 homolog A | Masra2 | OTTHUMP00000019745 | SARA1 | SAR1A_HUMAN | masra2 | OTTHUMP00000019744 | COPII-associated small GTPase

SAR1A: A Potential Drug Target and Biomarker

Sarcoma is a type of cancer that affects the body's connective tissue, and it is often treated with chemotherapy. However, the treatment can be expensive and often has limited success in terms of controlling the disease. Therefore, there is a need for new treatments that can provide more effective relief from sarcoma.

SAR1A is a protein that is expressed in sarcoma cells and has been shown to promote the growth and survival of these cells. In addition, SAR1A has also been shown to be involved in the development of resistance to chemotherapy in sarcoma cells.

Research has suggested that targeting SAR1A with drugs or other therapeutic agents could be an effective way to treat sarcoma. This is because SAR1A plays a key role in the development and progression of sarcoma, and targeting it with drugs could potentially inhibit its activity and reduce the growth of cancer cells.

One potential approach to targeting SAR1A is to use small molecules, such as inhibitors, to disrupt its activity. Researchers have identified a number of small molecules that have been shown to interact with SAR1A and may be effective in inhibiting its activity. These molecules include inhibitors of the SAR1A receptor, such as 尾-actinin andTrusted Source(986552-23-9).

Another potential approach to targeting SAR1A is to use antibodies, such as those that are designed to recognize and target specific regions of the protein. Researchers have shown that antibodies can be effective in inhibiting SAR1A activity and may be a promising approach to treating sarcoma.

In addition to these direct approaches, researchers have also suggested that targeting SAR1A may be an effective way to treat sarcoma by inhibiting the activity of other proteins that are involved in its development. For example, studies have shown that SAR1A is involved in the development of resistance to chemotherapy in sarcoma, and that inhibiting its activity with drugs or other therapeutic agents could potentially improve the effectiveness of chemotherapy.

Overall, SAR1A is a protein that has been shown to play a key role in the development and progression of sarcoma. Targeting SAR1A with small molecules or antibodies may be an effective way to treat this type of cancer. Further research is needed to determine the most effective approach to treating sarcoma with SAR1A and to develop new treatments that can provide more effective relief from this debilitating and often deadly form of cancer.

(c) 2023 The Author(s)

SAR1A is a protein that has been shown to play a key role in the development and progression of sarcoma. Targeting SAR1A with small molecules or antibodies may be an effective way to treat this type of cancer. Further research is needed to determine the most effective approach to treating sarcoma with SAR1A and to develop new treatments that can provide more effective relief from this debilitating and often deadly form of cancer.

Protein Name: Secretion Associated Ras Related GTPase 1A

Functions: Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES)

The "SAR1A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SAR1A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SAR1B | SARAF | SARDH | SARM1 | SARNP | SARS1 | SARS2 | SART1 | SART3 | SASH1 | SASH3 | SASS6 | SAT1 | SAT1-DT | SAT2 | SATB1 | SATB1-AS1 | SATB2 | SATB2-AS1 | SATL1 | SAV1 | SAXO1 | SAXO2 | SAYSD1 | SBDS | SBDSP1 | SBF1 | SBF1P1 | SBF2 | SBF2-AS1 | SBK1 | SBK2 | SBK3 | SBNO1 | SBNO2 | SBSN | SBSPON | SC5D | SCAANT1 | SCAF1 | SCAF11 | SCAF4 | SCAF8 | SCAI | SCAMP1 | SCAMP1-AS1 | SCAMP2 | SCAMP3 | SCAMP4 | SCAMP5 | SCAND1 | SCAND2P | SCAND3 | SCAP | SCAPER | SCARA3 | SCARA5 | SCARB1 | SCARB2 | SCARF1 | SCARF2 | SCARNA1 | SCARNA10 | SCARNA11 | SCARNA12 | SCARNA13 | SCARNA14 | SCARNA15 | SCARNA16 | SCARNA17 | SCARNA18 | SCARNA2 | SCARNA20 | SCARNA21 | SCARNA22 | SCARNA23 | SCARNA27 | SCARNA28 | SCARNA3 | SCARNA4 | SCARNA5 | SCARNA6 | SCARNA7 | SCARNA8 | SCARNA9 | SCARNA9L | SCART1 | SCAT1 | SCCPDH | SCD | SCD5 | SCDP1 | SCEL | SCF (SKP1-CUL1-F-box protein) Ubiquitin Ligase Complex | SCF Ubiquitin Ligase Complex | SCFD1 | SCFD2 | SCG2 | SCG3 | SCG5