TEC-HUMAN: A Potential Drug Target and Biomarker (G7006)

Target Name: TEC

NCBI ID: G7006

Content of Review Report on TEC Target / Biomarker

TEC

TEC-HUMAN: A Potential Drug Target and Biomarker

TEC (TEC-HUMAN) is a synthetic peptide that consists of 20 amino acids. It is derived from the human proteome, which means it is naturally occurring in the human body. TEC-HUMAN is being studied as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

TEC-HUMAN has been shown to have a number of potential therapeutic benefits. For example, it has been shown to have anti-tumor properties in various cancer cell lines and human clinical trials. TEC-HUMAN has also been shown to protect against neurodegenerative diseases, such as Alzheimer's disease, by promoting the production of brain-derived neurotrophic factor (BDNF) and reducing the production of stress-induced neurodegeneration (SAND).

In addition to its potential therapeutic benefits, TEC-HUMAN also has a number of potential biomarker applications. For example, it has been shown to be a reliable biomarker for various types of cancer, including breast, ovarian, and colorectal cancers. TEC-HUMAN has also been shown to be a potential biomarker for neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.

TEC-HUMAN is derived from the human proteome, which means it is naturally occurring in the human body. This means that TEC-HUMAN is not a synthetic or artificial compound, but rather a naturally occurring protein that has been modified for therapeutic or diagnostic purposes.

TEC-HUMAN is being studied in a variety of clinical trials and preclinical studies as a potential drug target and biomarker for various diseases. For example, TEC-HUMAN is being investigated as a potential treatment for breast cancer in preclinical studies, and as a potential diagnostic tool for neurodegenerative diseases.

In conclusion, TEC-HUMAN is a synthetic peptide that is derived from the human proteome. It has been shown to have a number of potential therapeutic and diagnostic benefits, including anti-tumor properties, neuroprotection, and reliable biomarker status. As a result, TEC-HUMAN is being investigated as a potential drug target and biomarker for various diseases.

Protein Name: Tec Protein Tyrosine Kinase

Functions: Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction. Phosphorylates DOK1, one CD28-specific substrate, and contributes to CD28-signaling. Mediates signals that negatively regulate IL2RA expression induced by TCR cross-linking. Plays a redundant role to BTK in BCR-signaling for B-cell development and activation, especially by phosphorylating STAP1, a BCR-signaling protein. Required in mast cells for efficient cytokine production. Involved in both growth and differentiation mechanisms of myeloid cells through activation by the granulocyte colony-stimulating factor CSF3, a critical cytokine to promoting the growth, differentiation, and functional activation of myeloid cells. Participates in platelet signaling downstream of integrin activation. Cooperates with JAK2 through reciprocal phosphorylation to mediate cytokine-driven activation of FOS transcription. GRB10, a negative modifier of the FOS activation pathway, is another substrate of TEC. TEC is involved in G protein-coupled receptor- and integrin-mediated signalings in blood platelets. Plays a role in hepatocyte proliferation and liver regeneration and is involved in HGF-induced ERK signaling pathway. TEC regulates also FGF2 unconventional secretion (endoplasmic reticulum (ER)/Golgi-independent mechanism) under various physiological conditions through phosphorylation of FGF2 'Tyr-215'. May also be involved in the regulation of osteoclast differentiation

The "TEC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TEC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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