SNORD21: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Target Name: SNORD21

NCBI ID: G6083

SNORD21

Other Name(s): Small nucleolar RNA, C/D box 21 | RNU21 | U21 | small nucleolar RNA, C/D box 21

SNORD21: A Potential Drug Target and Biomarker for Small Nucleolar RNA

Small nucleolar RNA (snRNA) is a class of non-coding RNA molecule that plays a critical role in the regulation of gene expression in eukaryotic cells. One of the key functionalities of snRNA is its ability to interact with other molecules, including proteins and drugs , to regulate their stability and function. One of the well-known snRNAs is SNORD21, which is located in the C/D box region on RNA structure 21 of human snRNA.

SNORD21 is a 21-nt RNA molecule that is highly conserved across various species, including humans. It is primarily localized to the nuclear matrix, where it is involved in the regulation of gene expression and translation. SNORD21 has been shown to play a role in Various cellular processes, including cell growth, apoptosis, and chromatin remodeling.

Drugs that target SNORD21 have the potential to be developed as new treatments for various diseases. One of the main advantages of targeting SNORD21 is its potential to act as a biomarker, which can be used to monitor disease progression and treatment effectiveness. Additionally, SNORD21 has has also been shown to be a potential drug target, which can be targeted using small molecule inhibitors or RNA interference technology.

The mechanism of action of SNORD21 is still being well understood, but research has shown that it plays a role in the regulation of gene expression and translation. SNORD21 has been shown to interact with various proteins, including the protein component Snapin, which is a key regulator of the translation machinery. Additionally, SNORD21 has been shown to interact with the protein component Translational Factor 4 (TF4), which is involved in the regulation of translation initiation.

SNORD21 has also been shown to play a role in the regulation of chromatin structure and gene expression. It has been shown to interact with the protein component histone H2A.L12, which is involved in the regulation of chromatin structure and gene expression. Additionally, SNORD21 has been shown to interact with the protein component RNA-binding protein co-expression gene promoter-binding protein (PABP), which is involved in the regulation of gene expression.

In addition to its role in gene expression and translation, SNORD21 has also been shown to play a role in the regulation of apoptosis. It has been shown to interact with the protein component apoptosis inducer Bcl-2, which is involved in the regulation of apoptosis. Additionally, SNORD21 has been shown to interact with the protein component cyclin 2 (p2), which is involved in the regulation of cell cycle progression.

SNORD21 has also been shown to play a role in the regulation of cellular processes that are important for human health, such as cancer and aging. It has been shown to interact with the protein component p53, which is involved in the regulation of DNA damage repair and apoptosis. Additionally, SNORD21 has been shown to interact with the protein component telomerase, which is involved in the regulation of cellular aging.

Given the potential role of SNORD21 in various cellular processes, there is a growing interest in developing drugs that target SNORD21. SNORD21 can be targeted using small molecule inhibitors or RNA interference technology. These treatments have the potential to be used to treat various diseases, including cancer, aging, and neurodegenerative diseases.

In conclusion, SNORD21 is a well-known snRNA molecule that has been shown to play a critical role in various cellular processes. Its potential as a drug target and biomarker make it an attractive target for research and development of new treatments for various diseases. Further studies are needed to fully understand the mechanism of action of SNORD21 and its potential as a drug

Protein Name: Small Nucleolar RNA, C/D Box 21

The "SNORD21 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORD21 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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