MIR4448: A Drug Target / Disease Biomarker (G100616127)
MIR4448: A Drug Target / Disease Biomarker
MIR4448 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the MIR44 family of non-coding RNA-binding proteins, which are known for their ability to interact with RNA molecules. One of the unique features of MIR4448 is its ability to form a stable complex with the protein USP90, which is a known drug target and a potential therapeutic agent for various diseases, including cancer, neurodegenerative diseases, and chronic obstructive pulmonary disease (COPD).
The MIR4448-USP90 complex has been shown to play a role in a variety of physiological processes, including cell survival, metabolism, and inflammation. USP90 has been shown to promote the growth and survival of cancer cells, and MIR4448 has been shown to inhibit the metastatic potential of these cells. In addition, MIR4448 has also been shown to play a role in the regulation of metabolism, by promoting the translation of RNA into protein and the degradation of non-protein molecules.
The MIR4448-USP90 complex is also of interest in the context of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. USP90 has been shown to accumulate in the brains of individuals with these conditions, and MIR4448 has been shown to contribute to the pathology of these diseases. In addition, MIR4448 has also been shown to be involved in the regulation of inflammation, by interacting with the protein NF-kappa-B.
The potential therapeutic applications of MIR4448 and USP90 are vast and varied. For example, MIR4448 could be used as a drug target for cancer, by inhibiting the activity of USP90 and increasing the levels of MIR4448 in cancer cells. In addition, MIR4448 could also be used as a biomarker for the diagnosis and monitoring of neurodegenerative diseases, by increasing the expression of MIR4448 in these diseases.
In conclusion, MIR4448 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of MIR4448 in these processes and to develop effective therapies based on this protein.
Protein Name: MicroRNA 4448
The "MIR4448 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR4448 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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