MIR4499: A Potential Drug Target and Biomarker (G100616304)

MIR4499: A Potential Drug Target and Biomarker

Mir4499, a protein located in the endoplasmic reticulum (ER), has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and chronic obstructive pulmonary disease (COPD). Its unique structure and function make it an attractive target for drug development, with potential applications in drug delivery, targeting, and diagnostic applications.

MIR4499 is a 25kDa protein that localizes to the endoplasmic reticulum, where it plays a critical role in the regulation of protein stability and degradation. It is composed of a N-terminus, a transmembrane region, and an C-terminus. The N-terminus contains a putative GFP-like domain, which is known to interact with various signaling pathways, including the TGF-β pathway. The C-terminus contains a unique farnesylated cysteine residue, which is involved in the regulation of protein stability and may serve as a potential drug target or biomarker.

MIR4499's unique structure and function make it an attractive target for drug development. Its N-terminus, with its GFP-like domain, suggests a potential for protein-protein interactions, which may play a role in the regulation of stability and trafficking of other proteins. The farnesylated cysteine residue at the C-terminus may be a potential drug target or biomarker by itself, as it has been shown to play a role in various cellular processes, including cell signaling, protein stability, and transport.

MIR4499 has been shown to be involved in various cellular processes that are relevant to several diseases, including cancer, neurodegenerative disorders, and COPD. For example, MIR4499 has been shown to be involved in the regulation of microtubule dynamics, which are critical for cell division and transport of various molecules. In cancer, MIR4499 has been shown to play a role in the regulation of cell cycle progression and the maintenance of stem-like properties. In neurodegenerative disorders, MIR4499 has been shown to be involved in the regulation of protein stability and the maintenance of normal cellular homeostasis. In COPD, MIR4499 has been shown to be involved in the regulation of airway smooth muscle cell function and contribute to the pathogenesis of this disease.

MIR4499 has also been shown to be a potential biomarker for several diseases, including cancer, neurodegenerative disorders, and COPD. Its expression has been shown to be elevated in various diseases, including cancer, neurodegenerative disorders, and COPD. This suggests that MIR4499 may be a useful biomarker for these diseases and could potentially serve as a therapeutic target.

In conclusion, MIR4499 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function make it an attractive target for drug development, as it may be involved in the regulation of various cellular processes that are relevant to several diseases. Further research is needed to fully understand the role of MIR4499 in disease progression and to explore its potential as a drug target and biomarker.

Protein Name: MicroRNA 4499

The "MIR4499 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR4499 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MIR449A | MIR449B | MIR449C | MIR4500 | MIR4500HG | MIR4501 | MIR4504 | MIR4505 | MIR4506 | MIR4507 | MIR4508 | MIR4509-1 | MIR4509-2 | MIR4509-3 | MIR450A1 | MIR450A2 | MIR450B | MIR4510 | MIR4511 | MIR4512 | MIR4513 | MIR4514 | MIR4516 | MIR4519 | MIR451A | MIR451B | MIR452 | MIR4520-1 | MIR4520-2 | MIR4521 | MIR4524A | MIR4524B | MIR4525 | MIR4526 | MIR4527 | MIR4527HG | MIR4529 | MIR4530 | MIR4531 | MIR4533 | MIR4534 | MIR4535 | MIR4536-1 | MIR4536-2 | MIR4537 | MIR4538 | MIR4539 | MIR454 | MIR4540 | MIR455 | MIR4632 | MIR4633 | MIR4634 | MIR4635 | MIR4638 | MIR4639 | MIR4640 | MIR4641 | MIR4642 | MIR4644 | MIR4645 | MIR4646 | MIR4647 | MIR4648 | MIR4649 | MIR4650-1 | MIR4650-2 | MIR4651 | MIR4652 | MIR4653 | MIR4655 | MIR4656 | MIR4657 | MIR4658 | MIR4659A | MIR4659B | MIR466 | MIR4660 | MIR4661 | MIR4662A | MIR4663 | MIR4664 | MIR4665 | MIR4666A | MIR4666B | MIR4667 | MIR4668 | MIR4669 | MIR4670 | MIR4671 | MIR4672 | MIR4673 | MIR4674 | MIR4675 | MIR4676 | MIR4677 | MIR4679-1 | MIR4679-2 | MIR4680 | MIR4681