MIR4463: A Potential Drug Target and Biomarker (G100616389)
MIR4463: A Potential Drug Target and Biomarker
MIR4463, a protein encoded by the MySQL gene, is a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Its unique structure and function make it an attractive target for drug development.
MIR4463 is a 21-kDa transmembrane protein that plays a role in the intracellular signaling pathway known as the TGF-β pathway. This pathway is involved in various cellular processes, including cell growth, differentiation, and survival. MIR4463 is a critical component of this pathway, as it regulates the activity of the transcription factor, transforming growth factor 尾1 (TGF-β1), which plays a crucial role in promoting cellular growth and differentiation.
MIR4463 is a highly conserved protein, with significant sequence homology with other transmembrane proteins, including the PDGF receptor, EGFR, and NHERG-1. This conservation suggests that MIR4463 may have similar functions in different cell types and organisms.
MIR4463 functions as a negative regulator of TGF-β1. It inhibits the activity of TGF-β1 by binding to its intracellular domain, which leads to the inhibition of TGF-β1-mediated signaling pathways. This interaction between MIR4463 and TGF-β1 is critical for the regulation of cellular processes, including cell growth, differentiation, and survival.
MIR4463 has been shown to play a role in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. For example, MIR4463 has been shown to be downregulated in various types of cancer, including breast, ovarian, and colorectal cancer. This suggests that MIR4463 may be a potential drug target for these diseases.
In addition to its role in cancer, MIR4463 has also been shown to be involved in neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. These findings suggest that MIR4463 may be a potential drug target for the treatment of neurodegenerative disorders.
MIR4463 has also been shown to be involved in cardiovascular diseases, including hypertension and heart failure. These findings suggest that MIR4463 may be a potential drug target for the treatment of cardiovascular diseases.
In conclusion, MIR4463 is a protein that has significant potential as a drug target and biomarker. Its unique structure and function make it an attractive target for drug development. Further research is needed to fully understand the role of MIR4463 in various diseases and to develop effective treatments.
Protein Name: MicroRNA 4463
The "MIR4463 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR4463 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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