Target Name: MIR451B
NCBI ID: G100616273
Review Report on MIR451B Target / Biomarker Content of Review Report on MIR451B Target / Biomarker
MIR451B
Other Name(s): hsa-mir-451b | microRNA 451b | hsa-miR-451b | MicroRNA 451b

MIR451B: A Potential Drug Target and Biomarker

Mir451B, a protein encoded by the human gene Mir451B, is a non-coding RNA molecule that has been shown to play a role in various biological processes. The Mir451B gene has been identified as a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The Mir451B protein is a key regulator of microRNA (miRNA) expression, a class of non-coding RNAs that play a crucial role in post-transcriptional gene regulation. miRNA molecules are designed to target specific mRNAs for degradation or translation, and are involved in a wide range of cellular processes, including cell growth, differentiation, and survival.

Mir451B has been shown to play a negative role in the regulation of miRNA expression in various organisms, including humans. Studies have shown that Mir451B can interact with the miR-202 complex, a known regulator of miRNA expression, and can inhibit its activity. This interaction between Mir451B and miR-202 highlights the potential of Mir451B as a drug target.

In addition to its role in miRNA regulation, Mir451B has also been shown to play a role in the regulation of gene expression and cellular processes. Studies have shown that Mir451B can interact with various cellular signaling pathways, including TGF-β, PI3K, and NF-kappa-B. This interaction between Mir451B and these signaling pathways suggests that it may be involved in the regulation of cellular processes that are important for human health and disease.

The potential drug target for Mir451B is based on its role in the regulation of miRNA expression and its interaction with miR-202. miRNA-based therapies have been shown to be effective in treating a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Therefore, targeting Mir451B as a drug candidate could potentially lead to new treatments for a variety of diseases.

In conclusion, Mir451B is a protein that has been shown to play a role in various biological processes, including the regulation of miRNA expression and cellular signaling pathways. Its potential as a drug target and biomarker makes it an attractive candidate for further research and development. Further studies are needed to fully understand the role of Mir451B in disease and to develop effective treatments based on its potential as a drug.

Protein Name: MicroRNA 451b

The "MIR451B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR451B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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