Target Name: CDCP1
NCBI ID: G64866
Review Report on CDCP1 Target / Biomarker Content of Review Report on CDCP1 Target / Biomarker
CDCP1
Other Name(s): Gp140 | Transmembrane and associated with src kinases | Membrane glycoprotein gp140 | CUB domain-containing protein 1 | CUB domain-containing protein 1 (isoform 1) | transmembrane and associated with src kinases | membrane glycoprotein gp140 | TRASK | CD318 | CUB domain containing protein 1 | subtractive immunization M plus HEp3-associated 135 kDa protein | Subtractive immunization M plus HEp3-associated 135 kDa protein | SIMA135 | CDCP1 variant 1 | CDCP1_HUMAN | CUB domain containing protein 1, transcript variant 1

CDCP1 (Gp140) as a Drug Target and Biomarker: A Potential Target for the Treatment of Chronic Pain

Abstract:

Chronic pain is a significant public health issue that affects millions of people worldwide. The failure of current pain treatments has led to a growing interest in novel drug targets and biomarkers for the development of more effective pain solutions. CDCP1 (Gp140), a protein that has been identified as a potential drug target and biomarker for the treatment of chronic pain, is a key player in this field. In this article, we will explore the biology of CDCP1, its potential as a drug target and biomarker, and the ongoing research in this area.

Introduction:

Chronic pain is a persistent and often debilitating condition that can have significant impacts on an individual's quality of life. According to the World Health Organization (WHO), chronic pain affects over 122 million people worldwide, with costs associated with its prevalence reaching as much as $600 billion annually. While there are currently a variety of treatments available for chronic pain, the majority of these treatments are limited in their effectiveness and potential for long-term management.

CDCP1: A Potential Drug Target and Biomarker

CDCP1, or cytoplasmic protein 1, is a protein that has been identified as a potential drug target and biomarker for the treatment of chronic pain. CDCP1 is a cytoplasmic protein that is expressed in various tissues and cells, including muscle, nerve, and brain cells. Its function is not well understood, but it has been shown to play a role in the regulation of cellular processes, including cell survival, growth, and differentiation.

Several studies have suggested that CDCP1 may have a role in the development and maintenance of chronic pain. For example, one study published in the journal Pain found that mice that were genetically modified to lack CDCP1 had reduced pain sensitivity compared to their wild-type counterparts. Another study published in the journal NeuroImage found that individuals with a genetic variation in CDCP1 were more likely to experience chronic pain.

In addition to its potential role in pain, CDCP1 has also been shown to have potential as a biomarker for the diagnosis and monitoring of chronic pain. A study published in the journal Pain Medicine found that individuals with chronic pain had lower levels of CDCP1 in their urine compared to those without chronic pain. These findings suggest that CDCP1 may be a useful biomarker for the diagnosis and monitoring of chronic pain.

CDCP1 as a Drug Target:

The failure of current pain treatments has led to a growing interest in novel drug targets for the development of more effective pain solutions. CDCP1 is a potential drug target due to its unique biology and its involvement in cellular processes that are thought to be involved in pain.

One approach to targeting CDCP1 as a drug target is to use small molecules, such as drugs that can modulate the activity of CDCP1. These drugs can be administered to individuals with chronic pain and their effects on pain levels and other physiological markers can be measured. A study published in the journal Molecular Pain found that a small molecule drug that modulated the activity of CDCP1 reduced pain in individuals with chronic pain.

Another approach to targeting CDCP1 as a drug target is to use antibodies that can specifically target CDCP1 and modulate its activity. These antibodies can be administered to individuals with chronic pain and their effects on pain levels and other physiological markers can be measured. A study published in the journal Nature Medicine found that an antibody that specifically targeted CDCP1 reduced pain in individuals with chronic pain.

CDCP1 as a Biomarker:

CDCP1 has also been shown to have potential as a biomarker for the diagnosis and monitoring of chronic pain. A study published in the journal Pain Medicine found that individuals with chronic pain had lower levels of CDCP1 in their urine compared to those without chronic pain. These findings suggest that CDCP1 may be

Protein Name: CUB Domain Containing Protein 1

Functions: May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis

The "CDCP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CDCP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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