Target Name: DSN1
NCBI ID: G79980
Review Report on DSN1 Target / Biomarker Content of Review Report on DSN1 Target / Biomarker
DSN1
Other Name(s): Kinetochore-associated protein DSN1 homolog | DSN1, MIS12 kinetochore complex component | DSN1_HUMAN | DSN1 component of MIS12 kinetochore complex | KNL3 | dJ469A13.2 | DSN1 variant 5 | Kinetochore-associated protein DSN1 homolog (isoform 3) | DSN1 component of MIS12 kinetochore complex, transcript variant 2 | DSN1 variant 2 | Kinetochore-associated protein DSN1 homolog (isoform 1) | DSN1 component of MIS12 kinetochore complex, transcript variant 5 | hKNL-3 | DSN1, MIND kinetochore complex component, homolog | Kinetochore null 3 homolog | MIS13 | kinetochore null 3 homolog | C20orf172 | DSN1 homolog, MIS12 kinetochore complex component

DSN1: A Potential Drug Target and Biomarker for Trematode Parasites

Introduction

DSN1 (Kinetochore-associated protein DSN1 homolog) is a protein that has been identified as a potential drug target and biomarker for trematode parasites, which are a major cause of disease in many parts of the world. Trematode parasites are parasitic worms that feed on the blood of humans and animals, and they can cause a range of symptoms, including skin rashes, fatigue, and anemia. Currently, there are no effective treatments available for many trematode parasites, which makes them a significant public health burden.

DSN1: Structure and Function

DSN1 is a protein that is expressed in many different tissues and cells in the body, including the brain, spinal cord, and peripheral tissues. It is a 22 kDa protein that has a molecular weight of 40 kDa and a calculated pI of 9.6. DSN1 is located at the kinetochore, which is the protein structure that lies at the center of the mitotic spindle in eukaryotic cells. It is involved in the regulation of microtubule dynamics and stability, and has been implicated in a number of cellular processes, including cell division , migration, and differentiation.

DSN1 has been shown to play a role in the regulation of the mitotic spindle, which is the structure that lies at the center of the cell during mitosis. The spindle is composed of two sets of proteins that help to keep the chromosomes in the correct position during the cell division process. DSN1 has been shown to interact with the microtubules that make up the spindle, and it has been shown to regulate the movement of the chromosomes along the spindle.

DSN1 has also been shown to play a role in the regulation of the cytoskeleton, which is the structure that lies outside the cell membrane. The cytoskeleton helps to give shape and stability to the cell, and it is involved in many cellular processes, including cell division, migration, and regulation of the cell surface. DSN1 has been shown to interact with the cytoskeleton, and it has been shown to regulate the movement of the cell.

DSN1 has also been shown to play a role in the regulation of inflammation. It has been shown to interact with a variety of cytokines, which are proteins that are involved in the immune response. DSN1 has been shown to regulate the production of these cytokines, which may help to protect the body against infection.

DSN1: Potential Drug Target

The potential drug target for DSN1 is its role in the regulation of the mitotic spindle and the cytoskeleton. Currently, there are several drugs that are being developed to target DSN1 and its role in these processes. These drugs include:

1. Taxol: Taxol is a chemotherapy drug that is used to treat various cancers, including breast and ovarian cancers. It works by inhibiting the production of DNA, which is necessary for cell growth and division. Taxol has been shown to inhibit the production of DSN1, which may help to protect the cells from the effects of the drug.
2. Paclitaxel: Paclitaxel is another chemotherapy drug that is used to treat various cancers, including breast and ovarian cancers. It works by inhibiting the production of spindle tubulin, which is a protein that is involved in the regulation of the mitotic spindle . Paclitaxel has been shown to inhibit the production of DSN1, which may help to protect the cells from the effects of the drug.
3. Nocodazole: Nocodazole is an antiviral drug that is used to treat various viruses, including malaria and herpes simplex virus. It works by inhibiting the production of

Protein Name: DSN1 Component Of MIS12 Kinetochore Complex

Functions: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis

The "DSN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DSN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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