Target Name: CPZ
NCBI ID: G8532
Review Report on CPZ Target / Biomarker Content of Review Report on CPZ Target / Biomarker
CPZ
Other Name(s): metallocarboxypeptidase Z | MGC99682 | Epididymis secretory sperm binding protein | CPZ variant 2 | Carboxypeptidase Z | CPZ variant 1 | Metallocarboxypeptidase Z | VEZT/CPZ fusion | Carboxypeptidase Z isoform 1 precursor (isoform 1) | Carboxypeptidase Z, transcript variant 1 | epididymis secretory sperm binding protein | CBPZ_HUMAN | Carboxypeptidase Z, transcript variant 2 | carboxypeptidase Z | Carboxypeptidase Z isoform 2 precursor (isoform 2)

CPZ: Metalloendoperoxidase and Inflammation

CPZ (Metallocarboxypeptidase Z) is a protein that is expressed in various tissues throughout the body, including the brain, nervous system, and organs. It is a member of the Metalloendoperoxidase (MET) family, which includes enzymes that are involved in the metabolism of metals and other molecules.

One of the unique features of CPZ is its ability to catalyze the conversion of certain metals, such as arginine, to their respective carboxylates. This reaction is critical for the maintenance of cellular homeostasis and is a fundamental aspect of many cellular processes, including cell signaling , neurotransmission, and muscle contraction.

In addition to its role in cellular metabolism, CPZ has also been shown to play a key role in the regulation of inflammation and pain. It has been shown to be involved in the detoxification of harmful substances that can cause inflammation, such as reactive oxygen species (ROS) and other stressors.

CPZ has also been shown to play a role in the development and progression of certain diseases, including cancer. Studies have shown that high levels of CPZ are associated with an increased risk of cancer, and that inhibiting its activity may be a potential therapeutic approach for cancer treatment.

Despite its potential as a drug target or biomarker, CPZ is still not well understood, and much more research is needed to fully determine its functions and potential therapeutic applications.

In conclusion, CPZ is a fascinating protein that plays a critical role in many cellular processes and has been shown to be involved in a variety of diseases, including cancer. As more research is conducted to understand its functions, it may become a valuable drug target or biomarker for the development of new treatments.

Protein Name: Carboxypeptidase Z

Functions: Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing

The "CPZ Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CPZ comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CR1 | CR1L | CR2 | CRABP1 | CRABP2 | CRACD | CRACDL | CRACR2A | CRACR2B | CRADD | CRADD-AS1 | CRAMP1 | CRAT | CRAT37 | CRB1 | CRB2 | CRB3 | CRBN | CRCP | CRCT1 | Creatine Kinase | CREB1 | CREB3 | CREB3L1 | CREB3L2 | CREB3L3 | CREB3L4 | CREB5 | CREBBP | CREBL2 | CREBRF | CREBZF | CREG1 | CREG2 | CRELD1 | CRELD2 | CREM | CRH | CRHBP | CRHR1 | CRHR2 | CRIM1 | CRIM1-DT | CRIP1 | CRIP1P1 | CRIP2 | CRIP3 | CRIPAK | CRIPT | CRISP1 | CRISP2 | CRISP3 | CRISPLD1 | CRISPLD2 | CRK | CRKL | CRLF1 | CRLF2 | CRLF3 | CRLS1 | CRMA | CRMP1 | CRNDE | CRNKL1 | CRNN | CROCC | CROCC2 | CROCCP2 | CROCCP3 | CROT | CRP | CRPPA | CRPPA-AS1 | CRTAC1 | CRTAM | CRTAP | CRTC1 | CRTC2 | CRTC3 | CRTC3-AS1 | CRX | CRY1 | CRY2 | CRYAA | CRYAB | CRYBA1 | CRYBA2 | CRYBA4 | CRYBB1 | CRYBB2 | CRYBB2P1 | CRYBB3 | CRYBG1 | CRYBG2 | CRYBG3 | CRYGA | CRYGB | CRYGC | CRYGD | CRYGGP