Target Name: CRYBG2
NCBI ID: G55057
Review Report on CRYBG2 Target / Biomarker Content of Review Report on CRYBG2 Target / Biomarker
CRYBG2
Other Name(s): absent in melanoma 1-like protein | FLJ10040 | Absent in melanoma 1-like protein | Beta-gamma crystallin domain containing 2 | Beta/gamma crystallin domain-containing protein 2 | AIM1L | CRBG2_HUMAN | beta-gamma crystallin domain containing 2 | crystallin beta-gamma domain containing 2 | FLJ38020 | absent in melanoma 1 like | DKFZp434L1713 | Crystallin beta-gamma domain containing 2

CRYBG2: A Potential Drug Target and Biomarker for Melanoma

Melanoma is a type of skin cancer that is highly aggressive and can be fatal if left untreated. It is characterized by the rapid growth of skin cells that produce melanin, the pigment that gives skin its color. When melanoma develops, it can spread quickly to other parts of the body, making it a particularly dangerous and deadly form of cancer.

Despite advances in treatment, the survival rate for melanoma remains low, and there is a high demand for new and more effective treatments. One potential solution to this problem is CRYBG2, a protein that is expressed in high levels in melanoma cells.

CRYBG2 is a 21-kDa transmembrane protein that is involved in a variety of cellular processes, including cell signaling, DNA replication, and apoptosis (programmed cell death). It is expressed in high levels in melanoma cells and has been shown to be a useful biomarker for the disease.

One of the key reasons why CRYBG2 is a promising drug target for melanoma is its role in cell signaling. CRYBG2 has been shown to play a role in the regulation of cell proliferation and survival, as well as in the development of melanoma.

In addition, CRYBG2 has also been shown to be involved in the development of other types of cancer, including lung and breast cancer. This suggests that it may be a useful target for a range of cancers, not just melanoma.

Another potential advantage of CRYBG2 as a drug target is its stability. Unlike many other proteins, which can be easily broken down by enzymes, CRYBG2 is stable and resistant to degradation. This makes it a more promising target for drug development, as it is less likely to be depleted in the body and can be administered in higher doses.

In addition to its potential as a drug target, CRYBG2 has also been shown to be a useful biomarker for melanoma. Its high expression levels in melanoma cells make it a reliable indicator of the disease, even in the absence of other diagnostic tests. This makes it an attractive candidate for use as a diagnostic marker in combination with other tests.

Overall, CRYBG2 is a promising protein for drug development as a treatment for melanoma. Its role in cell signaling and its stability make it a promising target for drug developers, while its high expression levels in melanoma cells make it a reliable biomarker for the disease. Further research is needed to fully understand the potential of CRYBG2 as a drug target for melanoma and to develop safe and effective treatments.

Protein Name: Crystallin Beta-gamma Domain Containing 2

The "CRYBG2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CRYBG2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CRYBG3 | CRYGA | CRYGB | CRYGC | CRYGD | CRYGGP | CRYGN | CRYGS | CRYL1 | CRYM | CRYM-AS1 | Cryptochrome | Crystallin | CRYZ | CRYZL1 | CRYZL2P | CRYZL2P-SEC16B | CS | CSAD | CSAG1 | CSAG2 | CSAG3 | CSAG4 | CSDC2 | CSDE1 | CSE1L | CSF1 | CSF1R | CSF2 | CSF2RA | CSF2RB | CSF2RBP1 | CSF3 | CSF3R | CSGALNACT1 | CSGALNACT2 | CSH1 | CSH2 | CSHL1 | CSK | CSKMT | CSMD1 | CSMD2 | CSMD2-AS1 | CSMD3 | CSN1S1 | CSN1S2AP | CSN1S2BP | CSN2 | CSN3 | CSNK1A1 | CSNK1A1L | CSNK1A1P1 | CSNK1D | CSNK1E | CSNK1G1 | CSNK1G2 | CSNK1G2-AS1 | CSNK1G3 | CSNK2A1 | CSNK2A2 | CSNK2A3 | CSNK2B | CSPG4 | CSPG4P10 | CSPG4P11 | CSPG4P12 | CSPG4P13 | CSPG4P1Y | CSPG4P2Y | CSPG4P3Y | CSPG5 | CSPP1 | CSRNP1 | CSRNP2 | CSRNP3 | CSRP1 | CSRP2 | CSRP3 | CSRP3-AS1 | CST Complex | CST1 | CST11 | CST13P | CST2 | CST3 | CST4 | CST5 | CST6 | CST7 | CST8 | CST9 | CST9L | CST9LP1 | CSTA | CSTB | CSTF1 | CSTF2 | CSTF2T | CSTF3