CREM-2: A Protein Implicated in Multiple Diseases (G1390)

Target Name: CREM

NCBI ID: G1390

CREM

CREM-2: A Protein Implicated in Multiple Diseases

CREM (CREM-2) is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the family of transcription factors, which are proteins that regulate gene expression.

CREM-2 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. It has also been identified as a potential drug target for several diseases, including cancer and neurodegenerative diseases.

One of the key functions of CREM-2 is its role in cell signaling. It is a transcription factor that can activate the genes of other proteins, which can then cause changes in the way cells behave and function. This can include changes in the structure and function of the cell, as well as the production of specific proteins that can cause diseases.

One of the ways that CREM-2 is involved in cancer is its role in the development of neuroblastomas, which are a type of cancer that starts in the brain or spinal cord. Studies have shown that CREM-2 is often expressed in neuroblastomas, and that inhibiting its activity can lead to a reduction in the growth and spread of these tumors.

CREM-2 is also involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells, and are often associated with increased levels of CREM-2 in the brain.

In addition to its role in neurodegenerative diseases, CREM-2 has also been shown to be involved in autoimmune disorders. These are conditions in which the immune system attacks the body's own tissues, leading to a range of symptoms and conditions. Studies have shown that CREM-2 is often expressed in the immune cells of individuals with autoimmune disorders, and that inhibiting its activity can lead to a reduction in the symptoms of these conditions.

Overall, CREM-2 is a protein that has been shown to play a role in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a potential drug target, it is being studied for its potential to treat these conditions, and to create new treatments for a variety of diseases.

Protein Name: CAMP Responsive Element Modulator

Functions: Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550)

The "CREM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CREM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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