ZNF518B: A Potential Drug Target and Biomarker for Various Diseases
ZNF518B: A Potential Drug Target and Biomarker for Various Diseases
ZNF518B (Z518B_HUMAN), a protein encoded by the Zinc Finger Nucleotide (ZNF) gene, is a key regulator of cell proliferation and survival in various organisms, including humans. ZNF518B has been identified as a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
The ZNF gene is a member of the ZNF/TAZ family of proteins, which are involved in the regulation of DNA replication, transcription, and cell growth. The ZNF gene encodes a 21-kDa protein that plays a critical role in the regulation of gene expression and DNA replication.
ZNF518B is a 21-kDa protein that is expressed in various tissues and organs, including brain, spinal cord, heart, and muscle. It is highly conserved and has a similar structure to other ZNF proteins. ZNF518B is composed of a N-terminal transmembrane domain, a coiled-coil domain, and a C-terminal T-loop region.
The N-terminal transmembrane domain is the region that gives ZNF518B its unique structure and function. This domain is involved in the regulation of the activity of various enzymes, including the DNA-binding proteins DNMTAT and HDACs. It is also involved in the regulation of the transport of various molecules across the membrane, including proteins involved in cell signaling and signaling pathways.
The coiled-coil domain is a regions of the protein that can form helices, which can alter the conformation of the protein and influence its function. ZNF518B has a single coiled-coil domain that is responsible for its unique structure and function.
The C-terminal T-loop region is the region that gives ZNF518B its unique structure and function. This region is involved in the regulation of various cellular processes, including cell signaling, DNA replication, and apoptosis. It is also involved in the regulation of protein stability and interactions.
ZNF518B is involved in the regulation of various cellular processes, including cell signaling, DNA replication, and apoptosis. It is a key regulator of cell proliferation and survival, and is involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
In addition to its role in cell signaling and survival, ZNF518B is also involved in the regulation of DNA replication and gene expression. It is a critical regulator of the DNA-binding proteins DNMTAT and HDACs, which are involved in the regulation of DNA replication and gene expression.
ZNF518B is also involved in the regulation of apoptosis, which is a critical mechanism of cell death that is involved in the development and progression of various diseases, including cancer. It is a key regulator of apoptosis, and is involved in the regulation of the factors that influence apoptosis, including the Bcl-2 protein.
In conclusion, ZNF518B is a key regulator of cell proliferation and survival, and is involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function make it an attractive drug target, and its potential as a biomarker for various diseases make it a valuable tool for the development of new treatments.
Protein Name: Zinc Finger Protein 518B
Functions: Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes
The "ZNF518B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF518B comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568 | ZNF569 | ZNF56P | ZNF57 | ZNF570 | ZNF571 | ZNF571-AS1 | ZNF572 | ZNF573 | ZNF574 | ZNF575 | ZNF576 | ZNF577 | ZNF578 | ZNF579 | ZNF580 | ZNF582 | ZNF582-DT | ZNF583 | ZNF584 | ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B | ZNF589 | ZNF592 | ZNF593 | ZNF594 | ZNF594-DT | ZNF595 | ZNF596 | ZNF597 | ZNF598 | ZNF599 | ZNF600 | ZNF603P | ZNF605 | ZNF606 | ZNF607 | ZNF608 | ZNF609 | ZNF610 | ZNF611 | ZNF613 | ZNF614 | ZNF615 | ZNF616 | ZNF618 | ZNF619 | ZNF620 | ZNF621 | ZNF622 | ZNF623 | ZNF624 | ZNF625
